*
stanford arches
left navigation bar
Infinite Menus, Copyright 2006, OpenCube Inc. All Rights Reserved. Infinite Menus, Copyright 2006, OpenCube Inc. All Rights Reserved.
* *
 

Huntingtin Protein and Protein Aggregation
Part 4

What Causes the Onset of HD?



Does mutant huntingtin protein itself kill nerve cells?

Not directly. As we have seen, one way Htt indirectly leads to nerve cell damage and toxicity is through the formation of protein aggregates and neuronal inclusions. These structures can interfere with several crucial cellular proteins and systems. Researchers have explored a number of hypotheses regarding the mechanisms by which huntingtin aggregates cause cell dysfunction in HD.

prevback to chapter titlenext

Last Modified: 9-13-02


HOPES Logo

An educational product of HOPES, not to be used in place of medical care.
For more information about HOPES, click on the Logo.
To contact HOPES with comments or questions, click here.


You are HOPES site visitor number

 
corner  corner
corner corner
HDSA Honors
HDSA Award Logo

The "Giving a Voice to HD" Award
corner corner
corner corner
Interactive HOPES
More Interactive HOPES>>>
corner corner
corner corner
Search HOPES
corner corner
corner corner
Esperanzas/Espoirs/
Other Languages
corner corner
corner  corner
 About HOPES    Home    Site Search    Glossary    Contact Us   
corner  corner
DHTML Web Menu by OpenCube