The HOPES Timeline (Non-Flash, Part 4)

A Brief History of Huntington's Disease

Scenes 16-20

1972

Thomas L. Perry finds diminished levels of GABA in the brains of HD patients.

1973

John Meeks and Natalie Stein suggest that the HD allele causes premature aging.

1974

Milton Wexler establishes the Foundation for Research in Hereditary Disease, which will later become the Hereditary Disease Foundation.

1976

Joseph T. Coyle develops the first rat model of HD by using kainic acid. The rats exhibited HD-like symptoms such as decreased weight, motor dysfunction, brain atrophy, neuronal inclusions and other cognitive impairments.

1977

The Congressional Commission for the Control of Huntington´s Disease and Its Consequences is held to develop a comprehensive report on HD in the United States.

Click here to return to the main HOPES Timeline page.

Last Modified: 04/12/2007

An educational product of HOPES, not to be used in place of medical care. For more information about HOPES, click on the Logo. To contact HOPES with comments or questions, click here.