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The HOPES Timeline (Non-Flash, Part 4)

A Brief History of Huntington's Disease



Scenes 16-20

Fig R-22: Scene 161972

Thomas L. Perry finds diminished levels of GABA in the brains of HD patients.

Fig R-23: Scene 171973

John Meeks and Natalie Stein suggest that the HD allele causes premature aging.

Fig R-24: Scene 181974

Milton Wexler establishes the Foundation for Research in Hereditary Disease, which will later become the Hereditary Disease Foundation.

Fig R-25: Scene 191976

Joseph T. Coyle develops the first rat model of HD by using kainic acid. The rats exhibited HD-like symptoms such as decreased weight, motor dysfunction, brain atrophy, neuronal inclusions and other cognitive impairments.

Fig R-26: Scene 201977

The Congressional Commission for the Control of Huntington´s Disease and Its Consequences is held to develop a comprehensive report on HD in the United States.

 

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Last Modified: 05/22/2009


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