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Cancer is the second leading cause of death, only after cardiovascular diseases. There are more than 80 million people worldwide diagnosed with cancer and the five-year survival rate for cancer patients is less than sixty percent. Cancer also has an enormous economical impact on the society with an annual cost of over $100 billion in patient care and over $20 billion in therapeutic drugs. At the molecular level, cancer is caused by uncontrolled and excessive cell divisions. The rapid development of biomedical research in the past decade has elucidated several themes common to most cancer cells. This seminar course will review the current knowledge on the molecular basis of cancer and critically read relevant scientific literatures. Topics will include cell cycle regulation, telomere biology, oncogene, tumor suppressor gene, cell signaling, gene expression, apoptosis and angiogenesis. Students will read current literatures in cancer biology and lead seminar discussions. Prerequisite: High School Biology.