1. Mitotic Spindle Assembly in HeLa Cells (Spinning Disc Confocal Imaging of GFP-alpha-Tubulin)/(JCB 173: 879-891)
2. Mitotic Chromosome Congression and Segregation in HeLa Cells (Spinning Disc Confocal Imaging of GFP-H2B)/(JCB 173: 879-891)
3. FLIP Analysis on the Dynamics of the Mitotic Spindle in HeLa Cells Expressing GFP-alpha-Tubulin/(JCB 173: 879-891)
4. Aneuploidy in a Tumor Cell Generated by Premature Chromosome Segregation (GFP-H2B)/(JCB 173: 879-891)
5. Cytokinesis in a HeLa Cell (GFP-H2B + DIC)/(PNAS 102: 13158-13163)
6. Cytokinesis in an Ect2-Knockdown Cell (GFP-H2B + DIC)/(PNAS 102: 13158-13163)
7. Cytokinesis in a MgcRacGAP-Knockdown Cell (GFP-H2B + DIC)/(PNAS 102: 13158-13163)
8. Cytokinesis in a MKLP1-Knockdown Cell (GFP-H2B + DIC)/(PNAS 102: 13158-13163)
9. Cytokinesis in an Anillin-Knockdown Cell (DIC)/(JBC 280: 33516-33524)
10. Cell Abscission in a HeLa Cell (DIC, note the presence of the midbody matrix)/(MBoc 17: 3881-3896)
11. Cytokinesis in a Cep55-Knockdown Cell (DIC, note the lack of the midbody matrix)/(MBoc 17: 3881-3896)
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Function of the Microtubule-Associated Protein HURP in Mitosis - Knockdown of HURP (siHURP) Generates Persistent Unaligned Chromosomes (JCB 173: 879-891). |
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Polo-like Kinase (Plx1) in Spindle Checkpoint Responses - Plx1 is the 3F3/2 Kinase Associated with Untensed Kinetochores (JCB 170: 709-719). |
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Role of Centralspindlin (CS) in Cytokinesis - CS Controls the Localization of the Guanine Nucleotide Exchange Factor Ect2 (PNAS 102: 13158-13163). |
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Function of Ect2 in Initiation of Cytokinesis - Ect2 Controls the Assembly of the Cleavage Furrow during Cytokinesis (PNAS 102: 12158-12163). |
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Role of the Actin-Binding Protein Anillin in the Progression of Cytokinesis - Anillin Controls the Localization of Myosin to the Cleavage Furrow during Cytokinesis (JBC 280: 33516-33524). |
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Function of Anillin in the Progression of Cytokinesis - Anillin Targets RhoA to the Cleavage Furrow during Cytokinesis (JBC 280: 33516-33524). |
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Function of the Microtubule-Binding Protein Cep55 in Cytokinesis - Cep55 Organizes the Midbody Matrix Structure at the Terminal Stage of Cytokinesis (MBoC 17: 3881-3896). |
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Biochemical Activities of Cep55 - Recombinant Cep55 Directly Binds and Bundles Microtubules (MT) (MBoC 17: 3881-3896). |
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Function of Cep55 in Cell Abscission - Cep55 Controls Membrane Fusion at the Terminal Stage of Cytokinesis (MBoc 17: 3881-3896). |
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Function of the Checkpoint Protein Mad2 in Mitosis - Ecotopic expression of Mad2 in HeLa Cells. |
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Effect of Mad2 on Embryonic Cell Division - Ecotopic expression of Mad2 in Xenopus Embryos. |
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