Research interests of the Cleary Lab

Leukemia cells in blood

Our laboratory studies the molecular pathogenesis of cancer.  We have discovered several genes that are damaged by chromosomal translocations in human leukemias.  We are currently investigating the normal functions of these genes and their contributions to cancer employing a variety of experimental approaches that include biochemical techniques and in vitro cellular transformation assays as well as genetic analyses using transgenic and knockout mouse models.

Visit the links below for more information on our research interests.


 
Pbx1 ko studies