Chem 235 Syllabus

Week	Date	Class	Lab
1	1/6	Intro, Theory, NMR Hardware	300 VNMR Software Training
2	1/12,13	Lock, Shimming, Tuning; FT NMR, Vector Model, Data Acquisition	300 Check-out with Dr. Lynch/new 400 VNMRJ Training, Data Acquisition Problem Set 1
3	1/20	Data Acquistion/Processing	Data Acquisition Problem Set 1 Tuning training (on 500)
4	1/26,27	Relaxation; Chemical Shift, Scalar Coupling	Tuning training (on 500)
5	2/2,3	Decoupling, NOE, Inverse Detection	Inova 500: 1D 1H; T1; T2 (90 minutes)
6	2/9,10	Pulsed Field Gradients, 2D NMR, COSY, TOCSY	Inova 500: COSY (90 minutes)
7	2/17	HSQC, HMBC, ROESY, NOESY	Inova 600: TOCSY, HSQC, HMBC, ROESY (overnight acquisition)
8	2/23,24	NMR of Paramagnetics, Dynamics, Solvent Suppression	Inova 600: 15N HSQC, 15N HMBC (overnight acquisition)
9	3/2,3	Detection of Nuclei other than 1H, Diffusion NMR, 3D NMR, NMR of Macromolecules	Data Transfer/Processing (90 minutes)
10	3/9,10	New Methods, Macromolecule-ligand interactions, 3D structure determination with NMR, NMR of Solids, In Vivo NMR, Imaging	Data Processing (90 minutes)
Final		Project DUE March 20

Note there is no class on university holidays on Martin Luther King Day (1/19) and Presidents Day (2/16)