2008

Greer EL and Brunet A (2008) Signaling networks in aging. Journal of Cell Science. 121: 407-412. Abstract PDF Poster

Greer EL and Brunet A (2008) FoxO transcription factors in ageing and cancer. Acta Physiol (Oxf). 192: 19-28. Abstract

Salih DA and Brunet A (2008) FoxO transcription factors in the maintenance of cellular homeostasis during aging. Curr Opin Cell Biol. 20: 126-136. Abstract PDF

Calnan DR and Brunet A (2008). The FoxO code. Oncogene. 27: 2276-2288. Abstract PDF

2007

Brunet A (2007). Aging and cancer: killing two birds with one worm. Nature Genetics 39:1306-1307. Abstract PDF

Greer EL, Dowlatshahi D, Banko MR, Hoang K, Blanchard D and Brunet A (2007) An AMPK-FOXO pathway mediates the extension of lifespan induced by a novel method of dietary restriction in C. elegans. Current Biology 17:1646-56. Abstract PDF

Brunet A and Rando T (2007) From stem to stern. Nature 449:288-289. Abstract PDF

Greer EL, Oskoui PR, Banko, MR, Maniar JM, Gygi MP, Gygi SP, Brunet A (2007) The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. J. Biol. Chem. 282:30107-19. Abstract PDF

Carter ME , Brunet A. FOXO transcription factors. (2007) Current Biology 7(4): R113-114 . PDF

2005

Greer EL, Brunet A. FOXO transcription factors at the interface between longevity and tumor suppression. (2005) Oncogene 24(50):7410-25. Abstract PDF

Before 2005 (selected publications)

Brunet A, Sweeney L, Sturgill F, Chua K, Greer P, Lin Y, Tran H, Ross S, Mostoslavsky R, Cohen H, Hu L, Cheng H, Jedrychowsky M, Gygi S, Sinclair D, Alt F, Greenberg ME. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. (2004) Science 303:2011-5. Abstract PDF

Tran H., Brunet A., Griffith E., and Greenberg M.E. The Many Forks in FOXO’s Road. (2003) Science STKE. (172):RE5. Abstract PDF

Tran H, Brunet A, Grenier J, Datta S, Fornace Jr A, Distefano P, Chiang L, Greenberg M. DNA repair pathway stimulated by the Forkhead transcription factor FOXO3a (FKHRL1) through the GADD45 protein. (2002) Science 296:530-534. Abstract PDF

Brunet A, Kanai F, Stehn J, Xu J, Sarbassova D, Frangioni J, Dala S, DeCaprio J, Greenberg ME, Yaffe M. 14-3-3 Transits to the Nucleus and actively participates in dynamic nucleo-cytoplasmic transport. (2002) J. Cell Biol. 156:817-828. Abstract PDF

Brunet A., Park J., Tran H., Hu L.S., Hemmings B.A., Greenberg M.E. The protein kinase SGK mediates survival signals by phosphorylating the Forkhead transcription factor FKHRL1/FOXO3a. (2001) Mol. Cell Biol. 21:952-965. Abstract PDF

Brunet A, Datta S, Greenberg ME. Transcription-dependent and independent control of neuronal survival by the Pi3K-Akt signaling pathway. (2001) Curr. Opin. Neurobiol. 11: 297-305. Abstract PDF

Brunet A, Bonni A, Zigmond, M, Lin MZ, Juo P, Hu L, Anderson M, Arden K, Blenis J, Greenberg ME. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. (1999) Cell 96: 857-868. Abstract PDF

Bonni A., Brunet A., West A.E., Datta S.R., Takasu M.A., Greenberg M.E. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and transcription- independent mechanisms. (1999) Science, 286:1358-1362. Abstract PDF

Brunet A., Roux D., Lenormand P., Dowd S., Keyse S. and Pouysségur J. Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry. (1999) EMBO J. 18: 664-74. Abstract PDF

Brunet A. and Pouysségur J. Identification of MAP kinase domains by re-directing stress signals into growth factor responses. (1996) Science 272: 1652-1655. Abstract PDF