For a full list of publications, see Laura Attardi's PubMed citations.

Baron, S., Hoang, A., Vogel, H., and L.D. Attardi. (2012) Unimpaired Skin Carcinogenesis in Desmoglein 3 Knockout Mice. PLoSOne 7(11): e50024.

Dusek, R.L., Bascom, J.L., Vogel, H., Baron, S., Borowsky, A.D., Bissell, M.J., and L.D. Attardi. (2012) Deficiency of the p53/p63 Target Perp Alters Mammary Gland Homeostasis and Promotes Cancer. Breast Cancer Res.14(2): R65

Bieging, K.T. and L.D. Attardi. (2011) Deconstructing p53 Transcriptional Networks in Tumor Suppression. Trends Cell Biol. [Epub ahead of print]

Jiang, D., Brady, C.A., Johnson, T.M., Lee, E.Y., Park, E.J., Scott, M.P., and L.D. Attardi. (2011) Full p53 Transcriptional Activation Potential is Dispensable for Tumor Suppression in Diverse Lineages. PNAS 108(41): 17123-8.

Brady, C.A., Jiang, D., Spano Mello, S., Johnson, T.M., Jarvis, L.A., Kozak, M.M., Kenzelmann Broz, D., Basak, S., Park, E.J., McLaughlin, M.E., Karnezis, A.N., and L.D. Attardi. (2011) Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression. Cell 145(4): 571-583.

Dusek, R.L. and L.D. Attardi. (2011) Desmosomes: New Perpetrators in Tumor Suppression. Nat. Rev. Cancer 11(5): 317-23.

Renault, V.M., Thekkat, P.U., Hoang, K.L., White, J.L., Brady, C.A., Kenzelmann Broz, D., Venturelli, O.S., Johnson, T.M., Oskoui, P.R., Xuan, Z., Santo, E.E., Zhang, M.Q., Vogel, H., L.D. Attardi, and Brunet, A. (2011) The Pro-Longevity Gene FoxO3 is a Direct Target of the p53 Tumor Suppressor. Oncogene [Epub ahead of print]

Jheon, A.H., Mostowfi, P., Snead, M.L., Ihrie, R.A., Sone, E., Pramparo, T., L.D. Attardi, and Klein, O.D. (2011) PERP Regulates Enamel Formation via Effects on Cell-Cell Adhesion and Gene Expression. J. Cell Sci. 124(Pt 5): 745-54.

Beaudry, V.G., Jiang, D., Dusek, R.L., Park, E.J., Knezevich, S., Ridd, K., Vogel, H., Bastian, B.C., and L.D. Attardi. (2010) Loss of the p53/p63 Regulated Desmosomal Protein Perp Promotes Tumorigenesis. PLoS Genet. 6(10): e1001168.

Huarte, M., Guttman, M., Feldser, D., Garber, M., Koziol, M., Broz, D., Khalil, A.M., Zuk, O., Amit, I., Rabani, M., L.D. Attardi, Regev, A., Lander, E.S., Jacks, T., and Rinn, J.L. (2010) A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response. Cell 142: 409-419.

Brady, C.A. and L.D. Attardi. (2010) p53 at a Glance. J. Cell Sci. 123(15): 2527-2532.

Beaudry, V.G., Ihrie, R.A., Jacobs, S.B.R., Nguyen, B., Pathak, N., Park, E., and L.D. Attardi. (2010) Loss of the Desmosomal Component PERP Impairs Wound Healing In Vivo. Dermatol Res Pract. 2010: 759731.

Broz Kenzelmann, Daniela, and L.D. Attardi, In vivo analysis of p53 tumor suppressor function using genetically engineered mouse models. Carcinogenesis 31(8): 1311-8.

Fete, M., Vanbokhoven, H., Clements, S.E., McKeon, F., Roop, D.R., Koster, M.I., Missero, C., Attardi, L.D., Lombillo, V.A., Ratovitski, E., Julapalli, M., Ruths, D., Sybert, V.P., Siegfried, E.C., and A.F. Bree. International Research Symposium on Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate (AEC) Syndrome, Am J Med Genet: 149(9): 1885-93.

Beaudry, V.G., Pathak, N., Koster, M.I., and L.D. Attardi. Differential Perp Regulation by TP63 Mutants Provides Insight into AEC Pathogenesis, Am J Med Genet. 149(9): 1952-7.

Beaudry, V.G., and L.D. Attardi. (2009) SKP-ing TAp63: stem cell depletion, senescence, and premature aging. Cell Stem Cell 5(1):1-2.

Nguyen, B., Dusek, R.L., Beaudry, V., and L.D. Attardi. (2009) Loss of the Novel Desmosomal protein PERP enhances the phenotypic effects of Pemphigus Vulgaris Autoantibodies. J. Invest. Dermatol. 129(7):1710-8. * Selected for cover image.

McGowan, K.A., J.Z. Li, C.Y Park, V. Beaudry, H.K. Tabor, A.J. Sabnis, W. Zhang, H. Fuchs, M.H. de Angelis, R.M. Myers, L.D. Attardi and G.S. Barsh. (2008). Mutations in ribosomal proteins cause p53-mediated dark skin and pleiotropic effects. Nat. Genet.40(8):  963-70.

Basak, S., S.B. Jacobs, A.J. Krieg, N. Pathak, Q. Zeng, P. Kaldis, A.J. Giaccia and L.D. Attardi. (2008). The Metastasis-Associated Gene Prl-3 is a p53 Target Involved in Cell-Cycle Regulation. Mol. Cell. 30 (3): 303-314.

Johnson, T.M., K. Meade, N. Pathak, M.R. Marques, and L.D. Attardi. (2008). Knockin Mice Expressing a Chimeric p53 Protein Reveal Mechanistic Differences in How p53 Triggers Apoptosis and Senescence. Proc Natl. Acad. Sci USA 105(4): 1215-1220.

Wijnhoven, S.W.P., E.N. Speksnijder, X. Liu, E. Zwart, C.Th.M. van Oostrom, R.B. Beems, E.M. Hoogervorst, M.M. Schaap, L.D. Attardi, T. Jacks, H. van Steeg, J. Jonkers, and A. de Vries. (2007). Dominant-Negative but not Gain-of-Function Effects of a p53-R270H Mutation in Mouse Epithelium Tissue after DNA Damage. Cancer Res. 67(10):4648-4656.

Jacobs, S.B.R., S. Basak, J.I. Murray, N. Pathak, and L.D. Attardi. (2007). Siva is an Apoptosis-Selective p53 Target Gene Important for Neuronal Cell Death. Cell Death Differ. 14(7):1374-85.

Ihrie, R.A., R.T. Bronson, and L.D. Attardi (2006). Adult Mice Lacking the p53/p63 Target Gene Perp are not Predisposed to Spontaneous Tumorigenesis but Display Features of Ectodermal Dysplasia Syndromes. Cell Death Differ. 13(9), 1614-1618.

Johnson, T.M. and L.D. Attardi (2006). Dissecting p53 Tumor Suppressor Function in vivo through the Analysis of Genetically Modified Mice. Cell Death Differ. 13(6), 902-908.

Johnson, T.M. and L.D. Attardi (2006). Reply to Explaining the Biological Activity of Transactivation-Deficient p53 Variants. Nature Genetics 38, 396-397.

Marques, M.R., R.A. Ihrie, J.S. Horner, and L.D. Attardi (2006). The Requirement for Perp in Postnatal Viability and Epithelial Integrity Reflects an Intrinsic Role in Stratified Epithelia. J. Invest. Dermatol. 126(1), 69-73.

Attardi, L.D. and L.A. Donehower (2005). Probing p53 Biological Functions Through the Use of Genetically Engineered Mouse Models. Mutat Res.576(1-2), 4-21.

Marques, M.R., J. S. Horner, R.A. Ihrie, R.T. Bronson, and L.D. Attardi (2005). Mice Lacking the p53/p63 Target Gene Perp are Resistant to Papilloma Development. Cancer Research 65(15), 6551-6556.

Ihrie, R.A. and L.D. Attardi (2005). A New Perp in the Lineup: Linking p63 and Desmosomal Adhesion. Cell Cycle 4(7), 873-876.

Johnson, T.M. and L.D. Attardi (2005). p53QS: An Old Mutant Teaches Us New Tricks. Cell Cycle 4(6), 731-734.

Artandi, S.E. and L.D. Attardi (2005). Pathways Connecting Telomeres and p53 in Senescence, Apoptosis, and Cancer. Biochem Biophys Res Commun. 331(3), 881-890.

Ihrie, R.A., M.R. Marques, B.T. Nguyen, J.S. Horner, C. Papazoglu, R.T. Bronson, A.A. Mills, and L.D. Attardi (2005). Perp is a p63-Regulated Gene Essential for Epithelial Integrity. Cell 120(6), 843-856.

Brown, J.M. and L.D. Attardi (2005). The Role of Apoptosis in Cancer Development and Treatment Response. Nat Rev Cancer 5(3), 231-237.

Johnson, T.M., E.M. Hammond, A. Giaccia, and L.D. Attardi (2005). The p53QS Transactivation-Deficient Mutant Shows Stress-Specific Apoptotic Activity and Induces Embryonic Lethality. Nature Genetics 37(2), 145-152.

Attardi, L.D. (2005). The Role of p53-Mediated Apoptosis as a Crucial Anti-Tumor Response to Genomic Instability: Lessons from Mouse Models. Mutation Research 569(1-2), 145-157.

Ihrie, R.A. and L.D. Attardi (2004). Perp-Etrating p53-Dependent Apoptosis. Cell Cycle 3(3), 267-269.

Attardi, L.D., A. de Vries, and T. Jacks (2004). Activation of the p53-Dependent G1 Checkpoint Response in Mouse Embryo Fibroblasts Depends on the Specific DNA Damage Inducer. Oncogene 23(4), 973-980.

Attardi, L.D. and R.A. DePinho (2004). Conquering the Complexity of p53. Nature Genetics 36(1), 7-8.

Ihrie, R.A., E. Reczek, J.S. Horner, L. Khachatrian, J. Sage, T. Jacks, and L.D. Attardi (2003). Perp is a Mediator of p53-Dependent Apoptosis in Diverse Cell Types. Current Biology 13(22), 1985-1990.

Attardi, L.D., E.E. Reczek, C. Cosmas, E.G. Demicco, M.E. McCurrach, S.W. Lowe, and T. Jacks (2000). PERP, an Apoptosis-Associated Target of p53, is a Novel Member of the PMP-22/gas3 Family. Genes and Development 14(6), 704-718.

Attardi, L.D., S.W. Lowe, J. Brugarolas, and T. Jacks (1996). Transcriptional Activation by p53, but not Induction of the p21 Gene, is Essential for Oncogene-Mediated Apoptosis. EMBO J. 15(14), 3693-3701.

Sah, V.P., L.D. Attardi, G.J. Mulligan, B.O. Williams, R.T. Bronson, and T. Jacks (1995). A Subset of p53-Deficient Embryos Exhibit Exencephaly. Nature Genetics 10(2), 175-180.