Laura D. Attardi, Ph.D., Principal Investigator
Phone: (650)725-8424 Fax: (650)723-7382
Education: Ph.D., Molecular and Cell Biology, University of California, Berkeley, 1994 B.A., Biochemistry, Cornell University, 1988
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Email: attardi@stanford.edu |
Phone: (650)725-8424 Fax: (650)723-7382 |
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Education: Ph.D., Molecular and Cell Biology, University of California, Berkeley, 1994 B.A., Biochemistry, Cornell University, 1988 |
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| Stanford Profile: http://med.stanford.edu/profiles/Laura_Attardi/ | |
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Email: ssmello@stanford.edu |
| Phone: (650) 723-5261 | |
| Education: Ph.D., University of Sao Paulo, Brazil, 2006 M.Sc., University of Sao Paulo, Brazil, 2002 B.Sc., University of Sao Paulo, Brazil, 1998 |
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| Research Interests: p53 and Pancreas Cancer | |
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Email: pbgarcia@stanford.edu |
| Phone: (650) 723-5261 | |
| Education: Ph.D., Molecular and Cell Biology, University of California, Berkeley, 2012 B.S., Biology, Santa Clara University, 2004 |
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| Research Interests: Non-coding RNAs as Effectors of p53 Function | |
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Email: djiang@stanford.edu |
| Phone: (650) 723-5261 | |
Education: Ph.D., Human Genetics, Virginia Commonwealth University, 2007 |
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| Research Interests: Transactivation-deficient p53 Mutants | |
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Email: jlfrey@stanford.edu |
| Phone: (650) 723-5261 | |
Education: B.S., Biochemistry, University of Nebraska-Lincoln, 2007 |
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| Research Interests: Apoptosis-specific p53 Target Genes | |
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Email: kbieging@stanford.edu |
| Phone: (650) 723-5261 | |
| Education: Ph.D., Virology, Northwestern University, 2010 B.S., Biology, Macalester College, 2004 |
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| Research Interests: Understanding Mechanism of p53 Action | |
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Email: hyphage@stanford.edu |
| Phone: (650) 723-5261 | |
| Education: Ph.D., Molecular and Cell Biology, University of California, Berkeley, 2011 B.S., Biological Science, Seoul National University, 2005 |
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| Research Interests: p53 Genomics | |
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Email: rajnitin@stanford.edu |
| Phone: (650) 723-5261 | |
| Education: Ph.D., Genetics, Michigan State University, East Lansing, 2012 M.Sc., Molecular and Human Genetics, Banaras Hindu University, India, 2005 B.Sc., Biotechnology, Bangalore University, India, 2003 |
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| Research Interests: Identification and Characterization of Inhibitors of Acute DNA Damage Induced, p53-dependent Apoptosis Using Mouse Prostate Cancer Model | |
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Email: brian89@stanford.edu |
| Phone: (650) 723-5261 | |
| Education: B.A., Molecular and Cell Biology, University of California, Berkeley, 2012 | |
| Research Interests: p53 Tumor Suppressor | |
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Email: csinow@stanford.edu |
| Phone: (650) 723-5261 | |
| Education: Stanford University, Class of 2012 | |
| Research Interests: p53-regulated non-coding RNAs | |
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Email: mjin2@stanford.edu |
| Phone: (650) 723-5261 | |
| Education: Stanford University, Class of 2016 | |
| Research Interests: Understanding Mechanism of p53 Action | |
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Email: karinh@stanford.edu |
| Phone: (650) 724-0261 | |
| Education: B.S., Business Management, San Jose State University | |
Check out the lab photo gallery!
Lab Alumni - Cancer Biology Ph.D. Students
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Project: The p53/p63 Target Gene Perp is Required for Apoptosis, Development, and Adult Survival |
Publications: Ihrie, R.A., R.T. Bronson, and L.D. Attardi (2006). Adult Mice Lacking the p53/p63 Target Gene Perp are not Predisposed to Spontaneous Tumorigenesis but Display Features of Ectodermal Dysplasia Syndromes. Cell Death Differ. 13(9), 1614-1618. Ihrie, R.A. and L.D. Attardi (2005). A New Perp in the Lineup: Linking p63 and Desmosomal Adhesion. Cell Cycle 4(7), 873-876. Ihrie, R.A., M.R. Marques, B.T. Nguyen, J.S. Horner, C. Papazoglu, R.T. Bronson, A.A. Mills, and L.D. Attardi (2005). Perp is a p63-Regulated Gene Essential for Epithelial Integrity. Cell 120(6), 843-856. Ihrie, R.A. and L.D. Attardi (2004). Perp-Etrating p53-Dependent Apoptosis. Cell Cycle 3(3), 267-269. Ihrie, R.A., E. Reczek, J.S. Horner, L. Khachatrian, J. Sage, T. Jacks, and L.D. Attardi (2003). Perp is a Mediator of p53-Dependent Apoptosis in Diverse Cell Types. Current Biology 13(22), 1985-1990. |
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| Current Job: Assistant Professor, Cancer Biology, Vanderbilt University Medical Center | |
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Project: p53 Transactivation Domain Mutant Knock-In Mice Provide Novel Insight into p53 Tumor Suppressor Function |
Publications: Johnson, T.M., K. Meade, N. Pathak, M.R. Marques, and L.D. Attardi. (2008). Knockin Mice Expressing a Chimeric p53 Protein Reveal Mechanistic Differences in How p53 Triggers Apoptosis and Senescence. Proc Natl. Acad. Sci USA 105(4): 1215-1220. Johnson, T.M. and L.D. Attardi (2006). Dissecting p53 Tumor Suppressor Function in vivo through the Analysis of Genetically Modified Mice. Cell Death Differ. 13(6), 902-908. Johnson, T.M. and L.D. Attardi (2006). Reply to Explaining the Biological Activity of Transactivation-Deficient p53 Variants. Nature Genetics 38, 396-397. Johnson, T.M. and L.D. Attardi (2005). p53QS: An Old Mutant Teaches Us New Tricks. Cell Cycle 4(6), 731-734. Johnson, T.M., E.M. Hammond, A. Giaccia, and L.D. Attardi (2005). The p53QS Transactivation-Deficient Mutant Shows Stress-Specific Apoptotic Activity and Induces Embryonic Lethality. Nature Genetics 37(2), 145-152. |
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Current Job: Emergency Medicine Resident at Oregon Health & Science University |
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Project: Characterizing the Role of the p53/p63 Target Gene, Perp, in Epidermal Homeostasis and Cancer |
Publications: Beaudry, V.G., Jiang, D., Dusek, R.L., Park, E.J., Knezevich, S., Ridd, K., Vogel, H., Bastian, B.C., and L.D. Attardi. (2010) Loss of the p53/p63 Regulated Desmosomal Protein Perp Promotes Tumorigenesis. PLoS Genet. 6(10): e1001168. Beaudry, V.G., Ihrie, R.A., Jacobs, S.B.R., Nguyen, B., Pathak, N., Park, E., and L.D. Attardi. (2010) Loss of the Desmosomal Component PERP Impairs Wound Healing In Vivo. Dermatol Res Pract. 2010: 759731. Beaudry, V.G., Pathak, N., Koster, M.I., and L.D. Attardi. (2009) Differential Perp Regulation by TP63 Mutants Provides Insight into AEC Pathogenesis.Am J Med Genet. 149(9): 1952-7. Beaudry, V.G., and L.D. Attardi. (2009) SKP-ing TAp63: stem cell depletion, senescence, and premature aging. Cell Stem Cell 5(1):1-2. |
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Current Job: Market Planning Manager, Genentech |
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Project: p53 Transactivation-Domain Mutant Mice Reveal Context-Specific Differences in p53's Mechanism of Action |
Publications: Jiang, D., Brady, C.A., Johnson, T.M., Lee, E.Y., Park, E.J., Scott, M.P., and L.D. Attardi. (2011) Full p53 Transcriptional Activation Potential is Dispensable for Tumor Suppression in Diverse Lineages. PNAS. 108(41): 17123-8. Brady, C.A., Jiang, D., Spano Mello, S., Johnson, T.M., Jarvis, L.A., Kozak, M.M., Kenzelmann Broz, D., Basak, S., Park, E.J., McLaughlin, M.E., Karnezis, A.N., and L.D. Attardi. (2011) Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression. Cell 145(4): 571-583. Renault, V.M., Thekkat, P.U., Hoang, K.L., White, J.L., Brady, C.A., Kenzelmann Broz, D., Venturelli, O.S., Johnson, T.M., Oskoui, P.R., Xuan, Z., Santo, E.E., Zhang, M.Q., Vogel, H., L.D. Attardi, and Brunet, A. (2011) The Pro-Longevity Gene FoxO3 is a Direct Target of the p53 Tumor Suppressor. Oncogene 30(29): 3207-21. Brady, C.A. and L.D. Attardi. (2010) p53 at a Glance. J. Cell Sci. 123(15): 2527-2532. |
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| Current Job: Postdoctoral Fellow, Randy Peterson Lab, Massachusetts General Hospital | |
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Jennifer Horner |
Kristin Meade |
Michelle Marques |
Rebecca Ihrie, |
Bichchau Nguyen |
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Shashwati Basak, Ph.D. |
Tom Johnson, |
Lesley Jarvis, |
Navneeta Pathak |
Margie Kozak |
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Suzanne Jacobs, |
Veronica Beaudry, |
Colleen Brady, |
Eunice Park |
Heather Chou |
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Sylvain Baron, |
Rachel Dusek, |
Daniela K Broz, |
