COMPLIMENTARY TUTORIALS
Detailed Program (pdf) | Keynote Addresses
Complimentary Tutorials | Complimentary Lab Tours | Complimentary OpenSim Workshop
Podium presentation Instructions | Poster presentation InstructionsAll Tutorials are free and held in the James H. Clark Center on Stanford campus. (directions)
Tutorial 1
Wednesday, August 22, 1:00 PM - 3:00 PMBiomechanical Modeling and Simulation
Scott Delp, Ph.D.
Professor of Bioengineering, Mechanical Engineering, and Orthopaedic Surgery
Stanford University, CA
Computational models provide a framework for exploring the biomechanics and neural control of movement. In recent years, simulations of human and animal movement have become widely used to explore a range of basic scientific questions, study the mechanisms of various diseases, and assist in the design of medical devices. This tutorial will provide an introduction to musculoskeletal modeling and the application of simulations in the study of movement. Specifically, the tutorial will:
- motivate the use of simulations in studies of human and animal movement,
- review the components of a simulation, including models of muscle-tendon mechanics, musculoskeletal geometry, skeletal dynamics, and neural control,
- provide examples of simulations that have provided insight into important scientific questions and clinical problems,
- discuss some of the limitations of current simulations and suggest future research directions.
Tutorial 2
Wednesday, August 22, 3:00 PM - 5:15 PM
The Use of Molecular Biology in Biomechanics
Richard L. Lieber, Ph.D.
Professor of Orthopaedics and Bioengineering
UCSD and VA Medical Centers
La Jolla, CA
The scientific community has experienced a virtual explosion in applications of molecular biological methods to the fields of medicine, biotechnology, computing and engineering. All of the highest scientific impact papers from 1994-to date used molecular biology to understand transduction of information by cells. These papers could justifiably be considered within the purview of biomechanics. In this tutorial, the basic tenets of molecular biology will be presented including basic cell structure and the flow of information from DNA to RNA to proteins. The most common methods used to study cells and tissues will be reviewed including gene cloning, sequencing, blotting methods and the use of reverse transcription (RT) and the polymerase chain reaction (PCR). Finally, application of these methods will be illustrated using examples of vascular, muscle and ligament cell response to mechanical signals provided by applications of exercise, strain fields and temperature. The main point of this presentation is to demonstrate that molecular biological methods provide powerful tools for studying tissue response, but the careful mechanical characterization of cells, receptors and even isolated proteins remain within the area of expertise we know as biomechanics. This is a field on which we all should have great impact.
