transplant
immunobiology laboratory
Research Descriptions
Dr. Krams'
Research
Dr.
Martinez' ResearchMartinez OM, Rosen HR.
Basic concepts in transplant immunology.
Liver
Transpl. 2005 11(4):370-81.
Obara H, Nagasaki K, Hsieh CL, Ogura Y, Esquivel CO,
Martinez OM, Krams SM.
IFN-gamma,produced by NK cells that infiltrate liver allografts early after
transplantation, links the innate and adaptive immune responses.
Am
J Transplant. 2005 Sep;5(9):2094-103.
Hsieh CL, Ogura Y, Obara H, Ali UA, Rodriguez GM,
Nepomuceno RR, Martinez OM, Krams SM.
Identification, cloning, and characterization of a novel rat natural killer receptor,
RNKP30: a molecule expressed in liver allografts.
Transplantation. 2004 Jan 15;77(1):121-8.
Nepomuceno RR, Balatoni CE, Natkunam Y, Snow AL, Krams SM,
Martinez OM.
Rapamycin inhibits the interleukin-10 signal transduction pathway and the growth
of Epstein Barr virus B cell lymphomas.
Cancer Research. 2003 Aug 1;63(15): 4472-80.
Falco DA, Nepomuceno RR, Krams SM, Lee PP, Davis MM,
Salvatierra O, Alexander SR, Esquivel CO, Cox KL, Frankel LR, Martinez OM.
Identification of Epstein-Barr virus-specific CD8+ T lymphocytes in the
circulation of pediatric transplant recipients.
Transplantation. 2002 Aug 27;74(4):501-10.
Hsieh CL, Obara H, Ogura Y, Martinez OM, Krams SM.
NK cells and transplantation.
Transpl Immunol. 2002 May;9(2-4):111-4. Review.
Nepomuceno RR, Snow AL, Robert Beatty P, Krams SM, Martinez OM.
Constitutive activation of Jak/STAT proteins in Epstein-Barr virus-infected B-cell
lines from patients with posttransplant lymphoproliferative disorder.
Transplantation. 2002 Aug 15;74(3):396-402.
Chan KW, Hopke CD, Krams SM, Martinez OM.
CD30 expression identifies the predominant proliferating T lymphocyte population
in human alloimmune responses.
J Immunol. 2002 Aug 15;169(4):1784-91.
Millan MT, Natkunam Y, Clarke-Katzenberg R, Desai D, Prapong W, So
SK, Esquivel CO, Sibley R, Ferran C, Martinez OM.
Epstein-Barr virus infection is associated with endothelial Bcl-2 expression in
transplant liver allografts.
Transplantation. 2002 Feb 15;73(3):465-9.
Krams SM.
New approaches to inducing the death of alloreactive lymphocytes.
Clin Exp Immunol. 2001 Dec;126(3):371-3. Review.
Snow AL, Chen LJ, Nepomuceno RR, Krams SM, Esquivel CO, Martinez OM.
Resistance to Fas-mediated apoptosis in EBV-infected B cell lymphomas is due to
defects in the proximal Fas signaling pathway.
J Immunol. 2001 Nov 1;167(9):5404-11.
Ogura Y, Martinez OM, Villanueva JC, Tait JF, Strauss HW, Higgins
JP, Tanaka K, Esquivel CO, Blankenberg FG, Krams SM.
Apoptosis and allograft rejection in the absence of CD8+ T cells.
Transplantation. 2001 Jun 27;71(12):1827-34.
Fox CK, Furtwaengler A, Nepomuceno RR, Martinez OM, Krams SM.
Apoptotic pathways in primary biliary cirrhosis and autoimmune hepatitis.
Liver. 2001 Aug;21(4):272-9.
Ogura Y, Krams SM, Martinez OM, Kopiwoda S, Higgins JP, Esquivel CO,
Strauss HW, Tait JF, Blankenberg FG.
Radiolabeled annexin V imaging: diagnosis of allograft rejection in an
experimental rodent model of liver transplantation.
Radiology. 2000 Mar;214(3):795-800.
Martinez OM, Krams SM.
Involvement of Fas-Fas ligand interactions in graft rejection.
Int Rev Immunol. 1999;18(5-6):527-46. Review.