Material Transfer Agreements (MTAs)

MTAs are short contracts governing the transfer of tangible research property (often biological materials) for in vitro research use.  When academic colleagues share research materials with each other, the Uniform Biological Material Transfer Agreement (also known as the UBMTA) ( http://www.niehs.nih.gov/techxfer/ubmta.htm) can be used since Stanford is a signatory, as are many universities. NIH has endorsed the use of the UBMTA.  Please refer to Policies for questions that arise with MTAs. 

For MTAs involving human stem cells, please see Research with Human Stem Cells below.


Incoming MTAs

Incoming MTAs govern the transfer of material from another organization to Stanford. Many companies and non-profit organizations ("Providers") require an MTA before they will share their materials. All incoming MTAs must be reviewed by ICO.  Investigators must complete a Material Transfer Agreement (MTA) Routing Form and have it signed by the Principal Investigator even when a UBMTA is involved.



Generally, two signatures are required on an incoming MTA to ensure that both the Provider and Stanford agree to the terms of the MTA. Typically, the Principal Investigator receiving the materials is also required to sign acknowledgement of the terms.

View Procedure for Incoming MTAs


Outgoing MTAs

Outgoing MTAs govern the transfer of materials for research purposes from Stanford to researchers outside of Stanford (at either non-profit organizations or industry). Stanford encourages researchers to share materials with other research colleagues without an MTA when possible.  It is always appropriate to ask the recipient not to share the materials without permission from the provider but this request does not require a formal document like an MTA. If a researcher feels that she or he is being asked for material that may have commercial value and could be licensable to industry, please contact OTL.

Transferring Human Tissues


Investigators are required to use an MTA when they transfer human tissues or human blood samples to a non-profit organization or company. Investigators must complete a Human Tissues Agreement (HTA) Routing Form and have it signed by the Principal Investigator. The HTA Routing Form may be sent to ICO by fax or campus mail. These transfers require review by the IRB, and these MTAs must be signed in advance by ICO. Templates for these MTAs are below.

Transferring Other Materials


For the transfer of other materials out from Stanford, an MTA is not required; however ICO provides template agreements for these transfers (below) and assistance as needed.

Certain types of materials require approval by research compliance panels under University policy before they may be sent out. For more information, see IRB, A-PLAC, Biosafety and Radiation.

Outgoing MTA Templates

 

Master MTAs

Master MTAs govern the ongoing transfer of material between Stanford and other organizations. With each transfer, the Master MTA terms and conditions remain the same and typically, the specifics of each transfer are documented in an Exhibit to the Master. Stanford has Master MTAs in place with StemCells, Inc., Rigel Pharmaceuticals, Inc., Genentech, and Kosan Biosciences.

Research with Human Stem Cells

Research involving human adult, fetal, or embryonic stem cells requires compliance with special state and federal regulations. Please note that research with federally approved (“registered”) human stem cells may be done with federal funding; however, research with non-registered human stem cells may not be done with federal funding.  http://www.stanford.edu/dept/DoR/rph/10-7.html

 

  • All human stem cell research projects, including those with adult stem cells, must be reviewed and approved in advance by Stanford’s Stem Cell Research Oversight Committee (SCRO).  http://www.stanford.edu/dept/DoR/scro/   

 

  • If you have questions, please contact the SCRO Manager, Kathryn Melsop (melsop@stanford.edu). 
  • If your research involves human embryonic stem cells, or embryos, please also complete the HESCRT form and attach it to the SU-42 routing form:  http://med.stanford.edu/rmg/forms.html (or attach it to the Material Transfer Agreement (MTA) routing form, if your project has already been awarded).

In order to receive human stem cells from laboratories outside Stanford, you must have a fully executed  MTA in place.  ICO handles these and other MTAs for Stanford researchers.  For more information, please see the MTA section of the ICO website. http://www.stanford.edu/group/ICO/forms/index.htm

WiCell Research Institute’s National Stem Cell Bank (NSCB) is one of several groups that provide stem cell lines to researchers.  Stanford and WiCell have entered into a Memorandum of Understanding (MOU), for the transfer of lines from WiCell to Stanford.

View Procedure to obtain WiCell lines from the WiCell Research Institute

The Stanford-WiCell MOU also allows Stanford researchers to distribute WiCell lines to other Stanford researchers. 

View Procedure to obtain WiCell lines from within Stanford

If you have any questions, please contact the Stanford University Institute for Stem Cell Biology and Regenerative Medicine ( stemcellinstitute@med.stanford.edu or call 650-736-8325), ICO (ico@otlmail.stanford.edu or call 650-723-0651) or the SCRO Manager (melsop@stanford.edu).


Article From The Scientist

Buffalo Case Highlights MTAs: Material transfer agreements can be misunderstood or considered an annoyance, say officials (http://www.the-scientist.com/article/display/22335/)

 

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Sponsored Research Agreements (SRAs)


Stanford uses Sponsored Research Agreements (SRAs) for research funded by industry. ICO negotiates these agreements when industrial sponsors provide funding to the university for a specific project and the sponsor expects intellectual property rights or reports from the research. Before negotiating these agreements, ICO will ordinarily meet with the Principal Investigator. For more information, please refer to our Sponsored Research Agreement Template. For international contracts, please refer to our Global Sponsored Research Agreement Template.

View Procedure for SRAs

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Collaboration Agreements

In a Collaboration Agreement, both parties agree to contribute resources and work together to find an answer to a particular research inquiry. Normally collaborators do not provide funding, but they contribute substantial materials, equipment, personnel, or specialized expertise to the project, while Stanford provides expertise, laboratory facilities and perhaps materials. Before negotiating these agreements, ICO will ordinarily meet with the Principal Investigator. For more information, please refer to our Collaboration Agreement template.

View Procedure for Collaboration Agreements

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Master Agreements

Master Agreements, sometimes called "blanket" or "umbrella" agreements, are used when a company expects to sponsor multiple projects with Stanford over a long period of time. In such cases, we pre-negotiate the legal terms and conditions of the agreement. When a new project is proposed, the terms of the Master Agreement are incorporated by reference, and only the statement of work/protocol, time period, and budget change. These agreements save time and help ensure that the contract is awarded efficiently. We currently have master agreements for sponsored research with ABB, Agilent, Amgen, Boeing, Bosch, Daimler Chrysler, Exxon Mobil Exploration Co., General Electric, General Motors, Hewlett-Packard, Kodak, Nokia, SAP, Siemens, Varian and Volkswagen of America.

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Amendments

An MTA, SRA, or Collaboration Agreement may require amending if there are changes to the research project such as a new PI, a revised statement of work, or a change in performance period. Amendments are also used to incorporate additional materials and/or funding (in the case of sponsored research).

View Procedure for Amendments

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