|
ICO handles four main types of contracts between Stanford University
and Industry: Material Transfer Agreements*, Sponsored Research Agreements, Collaboration
Agreements, and Master Agreements.
ICO also handles Amendments to
these agreements. For other agreements, please refer to Transactions
Handled by Other Offices at Stanford.
* Includes Material Transfer Agreements with
non-profits and government agencies.
Material Transfer Agreements (MTAs)
MTAs are short contracts governing the transfer
of tangible research property (often biological materials) for in
vitro research use. When academic colleagues share research materials with each other, the Uniform Biological Material Transfer Agreement (also known as the UBMTA) ( http://www.niehs.nih.gov/techxfer/ubmta.htm) can be used since Stanford is a signatory, as are many universities. NIH has endorsed the use of the UBMTA. Please
refer
to Policies for questions that arise with MTAs.
For MTAs involving human stem cells, please see Research with Human Stem Cells below.
Incoming MTAs
Incoming MTAs govern the transfer of material from
another organization to Stanford. Many companies and non-profit
organizations ("Providers") require an MTA before they
will share their materials. All incoming MTAs must be reviewed by
ICO. Investigators
must complete a Material Transfer Agreement (MTA) Routing Form and have it signed by the Principal Investigator even when a UBMTA is involved.
Generally, two signatures are required on an incoming MTA to ensure
that both the Provider and Stanford agree to the terms of the
MTA.
Typically, the Principal Investigator receiving the materials is
also required to sign acknowledgement of the terms.
View Procedure for Incoming MTAs
Outgoing MTAs
Outgoing MTAs govern the transfer of materials for research
purposes from Stanford to researchers outside of Stanford (at either
non-profit organizations or industry). Stanford encourages researchers to share materials with other research colleagues without an MTA when possible. It is always appropriate to ask the recipient not to share the materials without permission from the provider but this request does not require a formal document like an MTA. If a researcher feels that she or he is being asked for material that may have commercial value and could be licensable to industry, please contact OTL.
Transferring Human Tissues
Investigators are required to use an MTA when they transfer human
tissues or human blood samples to a non-profit organization or company.
Investigators must complete a Human Tissues Agreement (HTA) Routing
Form and have it signed by the Principal Investigator. The HTA
Routing Form may be sent to ICO by fax or campus mail. These transfers
require review by the IRB, and these MTAs must be signed in advance
by ICO. Templates for these MTAs are below.
Transferring Other Materials
For the transfer of other materials out from Stanford, an MTA is
not required; however ICO provides template agreements for these
transfers (below) and assistance as needed.
Certain types of materials require approval by research compliance
panels under University policy before they may be sent out. For
more information, see IRB,
A-PLAC, Biosafety
and Radiation.
Outgoing MTA Templates
Master
MTAs
Master MTAs govern the ongoing transfer of material between Stanford
and other organizations. With each transfer, the Master MTA terms
and conditions remain the same and typically, the specifics of each
transfer are documented in an Exhibit to the Master. Stanford has
Master MTAs in place with StemCells, Inc., Rigel Pharmaceuticals,
Inc., Genentech, and Kosan Biosciences.
Research with Human Stem Cells
Research involving human adult, fetal, or embryonic stem cells requires compliance with special state and federal regulations. Please note that research with federally approved (“registered”) human stem cells may be done with federal funding; however, research with non-registered human stem cells may not be done with federal funding. http://www.stanford.edu/dept/DoR/rph/10-7.html
- All human stem cell research projects, including those with adult stem cells, must be reviewed and approved in advance by Stanford’s Stem Cell Research Oversight Committee (SCRO). http://www.stanford.edu/dept/DoR/scro/
- If you have questions, please contact the SCRO Manager, Kathryn Melsop (melsop@stanford.edu).
- If your research involves human embryonic stem cells, or embryos, please also complete the HESCRT form and attach it to the SU-42 routing form: http://med.stanford.edu/rmg/forms.html (or attach it to the Material Transfer Agreement (MTA) routing form, if your project has already been awarded).
In order to receive human stem cells from laboratories outside Stanford, you must have a fully executed MTA in place. ICO handles these and other MTAs for Stanford researchers. For more information, please see the MTA section of the ICO website. http://www.stanford.edu/group/ICO/forms/index.htm
WiCell Research Institute’s National Stem Cell Bank (NSCB) is one of several groups that provide stem cell lines to researchers. Stanford and WiCell have entered into a Memorandum of Understanding (MOU), for the transfer of lines from WiCell to Stanford. View Procedure to obtain WiCell lines from the WiCell Research Institute
The Stanford-WiCell MOU also allows Stanford researchers to distribute WiCell lines to other Stanford researchers.
View Procedure to obtain WiCell lines from within Stanford
If you have any questions, please contact the Stanford University Institute for Stem Cell Biology and Regenerative Medicine (
stemcellinstitute@med.stanford.edu or call 650-736-8325), ICO (ico@otlmail.stanford.edu or call 650-723-0651) or the SCRO Manager (melsop@stanford.edu).
Article From The Scientist
Buffalo
Case Highlights MTAs: Material
transfer agreements can be misunderstood or considered an annoyance,
say officials (http://www.the-scientist.com/article/display/22335/)
Sponsored Research Agreements (SRAs)
Stanford uses Sponsored Research Agreements (SRAs) for research funded by industry. ICO negotiates these agreements when industrial sponsors provide funding to the university for a specific project and the sponsor expects intellectual property rights or reports from the research. Before negotiating these agreements, ICO will ordinarily meet with the Principal Investigator. For more information, please refer to our Sponsored
Research Agreement Template. For international contracts, please
refer to our Global
Sponsored Research Agreement Template.
View Procedure for SRAs
Collaboration Agreements
In a Collaboration Agreement, both parties agree to
contribute resources and work together to find an answer to a particular
research inquiry. Normally collaborators do not provide funding,
but they contribute substantial materials, equipment, personnel,
or specialized expertise to the project, while Stanford provides
expertise, laboratory facilities and perhaps materials.
Before negotiating these agreements, ICO will ordinarily meet with the Principal Investigator. For more
information, please refer to our Collaboration
Agreement template.
View Procedure for Collaboration Agreements
Master Agreements
Master Agreements, sometimes called "blanket"
or "umbrella" agreements, are used when a company expects
to sponsor multiple projects with Stanford over a long period
of
time. In such cases, we pre-negotiate the legal terms and conditions
of the agreement. When a new project is proposed, the terms of
the
Master Agreement are incorporated by reference, and only the statement
of work/protocol, time period, and budget change. These agreements
save time and help ensure that the contract is awarded efficiently.
We currently have master agreements for sponsored research with ABB, Agilent,
Amgen, Boeing, Bosch, Daimler Chrysler, Exxon Mobil Exploration Co., General Electric, General Motors, Hewlett-Packard, Kodak, Nokia, SAP, Siemens, Varian and Volkswagen of America.
Amendments
An MTA, SRA, or Collaboration Agreement
may require amending if there are changes to the research project
such as a new PI, a revised statement of work, or a change in performance
period. Amendments are also used to incorporate additional materials
and/or funding (in the case of sponsored research).
View Procedure for Amendments
|