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Bulletin Archive

This archived information is dated to the 2008-09 academic year only and may no longer be current.

For currently applicable policies and information, see the current Stanford Bulletin.

Graduate courses in Mechanical Engineering

Primarily for graduate students; undergraduates may enroll with consent of instructor.

ME 201. Dim Sum of Mechanical Engineering

Introduction to research in mechanical engineering for M.S. students and upper-division undergraduates. Weekly presentations by current ME Ph.D. and second-year fellowship students to show research opportunities across the department. Strategies for getting involved in a research project. (Sheppard)

1 unit, Aut (Kuhl, E; Gardella, I)

ME 203. Design and Manufacturing

Prototype development techniques as an intrinsic part of the design process. Machining, welding, and casting. Manufacturing processes. Design aspects developed in an individual term project chosen, designed, and fabricated by students. Labs, field trips. Undergraduates majoring in Mechanical Engineering or Product Design must take course for 4 units. Limited enrollment with consent of instructor. Corequisite: 103D or CAD experience. Corequisite for WIM for Mechanical Engineering and Product Design majors: ENGR 102M. Recommended: 101.

4 units, Aut (Beach, D), Win (Beach, D)

ME 204. Bicycle Design and Frame-Building

Lecture/lab. The engineering and artistic execution of designing and building a bicycle frame. Fundamentals of bicycle dynamics, handling, and sizing. Manufacturing processes. Films, guest lecturers, field trips. Each student designs and fabricates a custom bicycle frame. Limited enrollment. Prerequisite: 203 or equivalent.

3 units, Spr (Connolly, R)

ME 206A. Entrepreneurial Design for Extreme Affordability

(Same as OIT 333.) Bass Seminar. Project course jointly offered by School of Engineering and Graduate School of Business. Students apply engineering and business skills to design product prototypes, distribution systems, and business plans for entrepreneurial ventures in developing countries for challenges faced by the world's poor. Topics include user empathy, appropriate technology design, rapid prototype engineering and testing, social technology entrepreneurship, business modeling, and project management. Weekly design reviews; final course presentation. Industry and adviser interaction. Limited enrollment via application; see http://extreme.stanford.edu.

4 units, Win (Patell, J; Beach, D)

ME 206B. Entrepreneurial Design for Extreme Affordability

(Same as OIT 334.) Bass Seminar. Project course jointly offered by School of Engineering and Graduate School of Business. Students apply engineering and business skills to design product prototypes, distribution systems, and business plans for entrepreneurial ventures in developing countries for challenges faced by the world's poor. Topics include user empathy, appropriate technology design, rapid prototype engineering and testing, social technology entrepreneurship, business modeling, and project management. Weekly design reviews; final course presentation. Industry and adviser interaction. Limited enrollment via application; see http://extreme.stanford.edu.

4 units, Spr (Patell, J; Beach, D)

ME 207. Negotiation

(Same as CEE 151, CEE 251, MS&E 285.) Negotiation styles and processes to help students conduct and review negotiations. Workshop format integrating intellectual and experiential learning. Exercises, presentations, live and field examples, and individual and small group reviews. Application required before first day of class; see Coursework.

3 units, Aut (Christensen, S), Spr (Christensen, S)

ME 208. Patent Law and Strategy for Innovators and Entrepreneurs

How to build a patent portfolio and avoid patent infringement. How to conduct a patent search. How to file a provisional patent application.

2-3 units, Aut (Schox, J)

ME 210. Introduction to Mechatronics

Technologies involved in mechatronics (intelligent electro-mechanical systems), and techniques to apply this technology to mecatronic system design. Topics include: electronics (A/D, D/A converters, op-amps, filters, power devices); software program design, event-driven programming; hardware and DC stepper motors, solenoids, and robust sensing. Large, open-ended team project. Limited enrollment. Prerequisites: ENGR 40, CS 106, or equivalents.

4 units, Win (Messana, M; Ohline, R)

ME 212. Calibrating the Instrument

For first-year graduate students in the Joint Program in Design. Means for calibrating the designer's mind/body instrument through tools including improvisation, brainstorming, creative imaging, educational kinesiology, and Brain Gym. Current design issues; guest speakers; shared stories; and goal setting.

1 unit, Aut (Edmark, J)

ME 216A. Advanced Product Design: Needfinding

Human needs that lead to the conceptualization of future products, environments, systems, and services. Field work in public and private settings; appraisal of personal values; readings on social ethnographic issues; and needfinding for a corporate client. Emphasis is on developing the flexible thinking skills that enable the designer to navigate the future. Prerequisites for undergraduates: 116 and 203, or consent of the instructor. Prerequisites for graduate students: 203 and 313, or consent of the instructor.

3-4 units, Win (Barry, M; Patnaik, D)

ME 216B. Advanced Product Design: Implementation

Summary project using knowledge, methodology, and skills obtained in Product Design major. Students implement an original design concept and present it to a professional jury. Prerequisite: 216A.

4 units, Spr (Burnett, W; Howard, R)

ME 218A. Smart Product Design Fundamentals

Lecture/lab. Team design project series on programmable electromechanical systems design. Topics: transistors as switches, digital and analog circuits, operational amplifiers, comparators, software design, programming in C. Lab fee. Limited enrollment.

4-5 units, Aut (Carryer, J)

ME 218B. Smart Product Design Applications

Lecture/lab. Second in team design project series on programmable electromechanical systems design. Topics: user I/O, timer systems, interrupts, signal conditioning, software design for embedded systems, sensors, actuators, noise, and power supplies. Lab fee. Limited enrollment. Prerequisite: 218A or passing the smart product design fundamentals proficiency examination.

4-5 units, Win (Carryer, J)

ME 218C. Smart Product Design Practice

Lecture/lab. Advanced level in series on programmable electromechanical systems design. Topics: inter-processor communication, system design with multiple microprocessors, architecture and assembly language programming for the PIC microcontroller, controlling the embedded software tool chain, A/D and D/A techniques, electronic manufacturing technology. Team project. Lab fee. Limited enrollment. Prerequisite: 218B.

4-5 units, Spr (Carryer, J)

ME 218D. Smart Product Design: Projects

Lecture/lab. Industrially sponsored project is the culmination of the Smart Product Design sequence. Student teams take on an industrial project requiring application and extension of knowledge gained in the prior three quarters, including prototyping of a final solution with hardware, software, and professional documentation and presentation. Lectures on electronic and software design, and electronic manufacturing techniques. Topics: chip level design of microprocessor systems, real time operating systems, alternate microprocessor architectures, and PCB layout and fabrication.

4 units, Aut (Carryer, J)

ME 219. The Magic of Materials and Manufacturing

Lecture/lab. Methods for market-quantity manufacturing of parts and products from a product designer's point of view. Materials including metals, plastics, ceramics, fibers, and foams, and processes that manipulate, exploit, transform, and modify these materials. Visual descriptions of processes, product examples, relevant material details, cost information, and manufacturability rules-of-thumb. Imagining and creating new products. Manufacturing site visits; laboratory projects. Enrollment limited to 20.

3 units, Spr (Beach, D; Johnson, K)

ME 220. Introduction to Sensors

Sensors are widely used in scientific research and as an integral part of commercial products and automated systems. The basic principles for sensing displacement, force, pressure, acceleration, temperature, optical radiation, nuclear radiation, and other physical parameters. Performance, cost, and operating requirements of available sensors. Elementary electronic circuits which are typically used with sensors. Lecture demonstration of a representative sensor from each category elucidates operating principles and typical performance. Lab experiments with off-the-shelf devices.

3-4 units, Spr (Staff)

ME 222. Design for Sustainability

Lecture/lab. Role of design in building a sustainable world. How to include sustainability in the design process considering environmental, cultural, and social impacts. Focus is on a proactive design approach, and the tools and techniques needed to translate theory into artifact.

2-3 units, Spr (Bishop, S; Boyle, D)

ME 227. Vehicle Dynamics and Control

The application of dynamics, kinematics, and control theory to the analysis and design of ground vehicle behavior. Simplified models of ride, handling, and braking, their role in developing intuition, and limitations in engineering design. Suspension design fundamentals. Performance and safety enhancement through automatic control systems. In-car laboratory assignments for model validation and kinesthetic understanding of dynamics. Limited enrollment. Prerequisites: ENGR 105, consent of instructor.

3 units, Spr (Gerdes, C)

ME 233. Making it Big: Crossing the Entrepreneur's Gap

Students take novel designs into entrepreneurial production and prepare for market production. Education, resources, and community to help cross the gap, found ideas and make them real in volume. Topics include entrepreneurial production methods and initiation, vendor selection and engagement, cost, design transfer, quality and testing, and manufacturing planning and execution. Leadership roles in entrepreneurial and large production-oriented companies. Case studies, project reviews, final presentation, industry interaction.

3 units, Aut (Theeuwes, M)

ME 238. Patent Prosecution

(Same as LAW 321.) Stages of the patent application process: identifying, capturing, and evaluating inventions; performing a patentability investigation, analyzing the documents, and the scope of the patent protection; composing claims that broadly cover the invention; creating a specification that supports the claims; filing a patent application with the U.S. Patent and Trademark Office; and analyzing an office action and preparing an appropriate response. Current rules and case law. Strategic decisions within each stage, such as: how does a patent application advance the patent portfolio; and in what countries should a patent application be filed?

2 units, Win (Schox, J)

ME 257. Turbine and Internal Combustion Engines

(Same as ME 357.) Principles of design analysis for aircraft gas turbines and automotive piston engines. Analysis for aircraft engines performed for Airbus A380 type aircraft. Design parameters determined considering aircraft aerodynamics, gas turbine thermodynamics, compressible flow physics, and material limitations. Additional topics include characteristics of main engine components, off-design analysis, and component matching. Performance of automotive piston engines including novel engine concepts in terms of engine thermodynamics, intake and exhaust flows, and in-cylinder flow.

3 units, Win (Pitsch, H)

ME 260. Fuel Cell Science and Technology

Emphasis on proton exchange membrane (PEM) and solid oxide fuel cells (SOFC), and principles of electrochemical energy conversion. Topics in materials science, thermodynamics, and fluid mechanics. Prerequisites: MATH 43, PHYSICS 55, and ENGR 30 or ME 140, or equivalents.

3 units, Spr (Prinz, F)

ME 261. Dynamic Systems

(Same as ME 161.) (Graduate students only enroll in 261.) Modeling, analysis, and measurement of mechanical and electromechanical systems. Numerical and closed form solutions of ordinary differential equations governing the behavior of single and multiple degree of freedom systems. Stability, resonance, amplification and attenuation, and control system design. Prerequisite: background in dynamics and calculus such as ENGR 15 and MATH 43. Recommended: CME 102, and familiarity with differential equations, linear algebra, and basic electronics.

3-4 units, Aut (Mitiguy, P)

ME 265. Technology Licencing and Commercialization

How to profit from technology; processes and strategies to commercialize functional or artistic inventions and creations (not limited to mechanical engineering). Business and legal aspects of determining what can be owned and licensed, how to determine commercial value, and what agreements are necessary. Contract and intellectual property law; focus is on provisions of license agreements and their negotiation.

3 units, Spr (Hustein, J)

ME 280. Skeletal Development and Evolution

The mechanobiology of skeletal growth, adaptation, regeneration, and aging is considered from developmental and evolutionary perspectives. Emphasis is on the interactions between mechanical and chemical factors in the regulation of connective tissue biology. Prerequisites: 80, or Human Biology core, or Biology core.

3 units, Spr (Carter, D)

ME 284A. Cardiovascular Bioengineering

(Same as BIOE 284A.) Via Internet. Bioengineering principles applied to the cardiovascular system. Anatomy of human cardiovascular system, comparative anatomy, and allometric scaling principles. Cardiovascular molecular and cell biology. Overview of continuum mechanics. Form and function of blood, blood vessels, and the heart from an engineering perspective. Normal, diseased, and engineered replacement tissues.

3 units, Aut (Taylor, C)

ME 284B. Cardiovascular Bioengineering

(Same as BIOE 284B.) Via Internet. Continuation of ME 284A. Integrative cardiovascular physiology, blood fluid mechanics, and transport in the microcirculation. Sensing, feedback, and control of the circulation. Overview of congenital and adult cardiovascular disease, diagnostic methods, and treatment strategies. Engineering principles to evaluate the performance of cardiovascular devices and the efficacy of treatment strategies.

3 units, Win (Taylor, C)

ME 287. Soft Tissue Mechanics

Structure/function relationships and mechanical properties of soft tissues, including nonlinear elasticity, viscoelasticity, and poroelasticity. Undergraduates require consent of instructor.

3 units, Win (Levenston, M)

ME 289. Biomechanical Engineering Research Semiar

BME research conducted at Stanford for incoming students. Graduate students and postdoctoral fellows present research emphasizing motivation of research questions, project design, methods, and preliminary results.

1 unit, not given this year

ME 294. Medical Device Design

In collaboration with the School of Medicine. Introduction to medical device design for undergraduate and graduate engineering students. Design and prototyping. Labs; medical device environments may include hands-on device testing; and field trips to operating rooms and local device companies. Limited enrollment. Prerequisite: 203.

3 units, Aut (Staff)

ME 297. Forecasting the Future of Engineering

Goal is to develop a 25-year forecast of the future of engineering including the challenges engineers are likely to be asked to solve, and how engineers can be prepared to meet these challenges. Students prepare a long-range forecast of a specific science/engineering sector and a proposed initiative tying new engineering capabilities with global challenges.

3 units, Win (Saffo, P; Benjamin, C)

ME 298. Silversmithing and Design

Skills involved in working with precious metals at a small scale. Investment casting and fabrication techniques such as reticulation, granulations, filigree, and mokume gane.

3-4 units, Win (Shaughnessy, S; Knox, A)

ME 299A. Practical Training

For master's students. Educational opportunities in high technology research and development labs in industry. Students engage in internship work and integrate that work into their academic program. Following internship work, students complete a research report outlining work activity, problems investigated, key results, and follow-up projects they expect to perform. Meets the requirements for curricular practical training for students on F-1 visas. Student is responsible for arranging own internship/employment and faculty sponsorship. Register under faculty sponsor's section number. All paperwork must be completed by student and faculty sponsor, as the Student Services Office does not sponsor CPT. Students are allowed only one quarter of CPT per degree program.

1 unit, Aut (Staff), Win (Staff), Spr (Staff), Sum (Staff)

ME 299B. Practical Training

For Ph.D. students. Educational opportunities in high technology research and development labs in industry. Students engage in internship work and integrate that work into their academic program. Following internship work, students complete a research report outlining work activity, problems investigated, key results, and follow-up projects they expect to perform. Meets the requirements for curricular practical training for students on F-1 visas. Student is responsible for arranging own internship/employment and faculty sponsorship. Register under faculty sponsor's section number. All paperwork must be completed by student and faculty sponsor, as the student services office does not sponsor CPT. Students are allowed only one quarter of CPT per degree program.

1 unit, Aut (Staff), Win (Staff), Spr (Staff), Sum (Staff)

ME 300A. Linear Algebra with Application to Enginering Computations

(Same as CME 200.) Solving matrix-vector systems. Direct and iterative solvers for non-singular linear systems of equations; their accuracy, convergence properties, and computational efficiency. Under- and over-determined systems, and nonlinear systems of equations. Eigenvalues, eigenvectors, and singular values; their application to engineering problems. Concepts such as basis, linear independence, column space, null space, rank, norms and condition numbers, projections, and matrix properties. Recommended: familiarity with computer programming; mathematics background equivalent to MATH 103, 130.

3 units, Aut (Gerritsen, M)

ME 300B. Partial Differential Equations in Engineering

(Same as CME 204.) Geometric interpretation of partial differential equation (PDE) characteristics; solution of first order PDEs and classification of second-order PDEs; self-similarity; separation of variables as applied to parabolic, hyperbolic, and elliptic PDEs; special functions; eigenfunction expansions; the method of characteristics. If time permits, Fourier integrals and transforms, Laplace transforms. Prerequisite: CME 200/ME 300A, equivalent, or consent of instructor.

3 units, Win (Shaqfeh, E)

ME 300C. Introduction to Numerical Methods for Engineering

(Same as CME 206.) Numerical methods from a user's point of view. Lagrange interpolation, splines. Integration: trapezoid, Romberg, Gauss, adaptive quadrature; numerical solution of ordinary differential equations: explicit and implicit methods, multistep methods, Runge-Kutta and predictor-corrector methods, boundary value problems, eigenvalue problems; systems of differential equations, stiffness. Emphasis is on analysis of numerical methods for accuracy, stability, and convergence. Introduction to numerical solutions of partial differential equations; Von Neumann stability analysis; alternating direction implicit methods and nonlinear equations. Prerequisites: CME 200/ME 300A, CME 204/ME 300B.

3 units, Spr (Moin, P)

ME 304. The Designer's Voice

How to develop a point of view about a design career in order to articulate a design vision, inspire a design studio, or infect a business with a culture of design thinking. Focus is on the integration of work and worldview, professional values, design language, and the development of the designer's voice. Role play, guest speakers, individual mentoring and coaching, student journals. Restricted to Joint Product in Design graduate students.

1 unit, Win (Burnett, W)

ME 308. Spatial Motion

The geometry of motion in Euclidean space. Fundamentals of theory of screws with applications to robotic mechanisms, constraint analysis, and vehicle dynamics. Methods for representing the positions of spatial systems of rigid bodies with their inter-relationships; the formulation of Newton-Euler kinetics applied to serial chain systems such as industrial robotics.

3 units, alternate years, not given this year

ME 309. Finite Element Analysis in Mechanical Design

Basic concepts of finite elements, with applications to problems confronted by mechanical designers. Linear static, modal, and thermal formulations; nonlinear and dynamic formulations. Students implement simple element formulations. Application of a commercial finite element code in analyzing design problems. Issues: solution methods, modeling techniques, features of various commercial codes, basic problem definition. Individual projects focus on the interplay of analysis and testing in product design/development. Prerequisite: MATH 103, or equivalent. Recommended: 80, or equivalent in structural and/or solid mechanics; some exposure to principles of heat transfer.

3 units, Spr (Kuhl, E)

ME 310A. Project-Based Engineering Design, Innovation, and Development

Three quarter sequence; for engineering graduate students intending to lead projects related to sustainability, automotive, biomedical devices, communication, and user interaction. Student teams collaborate with academic partners in Europe, Asia, and Latin America on product innovation challenges presented by global corporations to design requirements and construct functional prototypes for consumer testing and technical evaluation. Design loft format such as found in Silicon Valley consultancies. Typically requires international travel. Prerequisites: undergraduate engineering design project; consent of instructor.

5 units, Aut (Leifer, L; Cutkosky, M)

ME 310B. Project-Based Engineering Design, Innovation, and Development

(Same as ENGR 310B.) Three quarter sequence; for engineering graduate students intending to lead projects related to sustainability, automotive, biomedical devices, communication, and user interaction. Student teams collaborate with academic partners in Europe, Asia, and Latin America on product innovation challenges presented by global corporations to design requirements and construct functional prototypes for consumer testing and technical evaluation. Design loft format such as found in Silicon Valley consultancies. Typically requires international travel. Prerequisites: undergraduate engineering design project; consent of instructor.

5 units, Win (Leifer, L; Cutkosky, M)

ME 310C. Project-Based Engineering Design, Innovation, and Development

Three quarter sequence; for engineering graduate students intending to lead projects related to sustainability, automotive, biomedical devices, communication, and user interaction. Student teams collaborate with academic partners in Europe, Asia, and Latin America on product innovation challenges presented by global corporations to design requirements and construct functional prototypes for consumer testing and technical evaluation. Design loft format such as found in Silicon Valley consultancies. Typically requires international travel. Prerequisites: undergraduate engineering design project; consent of instructor.

5 units, Spr (Leifer, L; Cutkosky, M)

ME 312. Advanced Product Design: Formgiving

Lecture/lab. Small- and medium-scale design projects carried to a high degree of aesthetic refinement. Emphasis is on form development, design process, and model making. Prerequisites: 203, 313. Corequisite: ARTSTUDI 160.

3-4 units, Win (Burnett, W)

ME 313. Human Values and Innovation in Design

Introduction to the philosophy, spirit, and tradition of the product design program. Hands-on design projects used as vehicles for design thinking, visualization, and methodology. The relationships among technical, human, aesthetic, and business concerns. Drawing, prototyping, and design skills. Focus is on tenets of design philosophy: point of view, user-centered design, design methodology, and iterative design.

3 units, Aut (Banerjee, S)

ME 314. Good Products, Bad Products

The characteristics of industrial products that cause them to be successes or failures: the straightforward (performance, economy, reliability), the complicated (human and cultural fit, compatibility with the environment, craftsmanship, positive emotional response of the user), the esoteric (elegance, sophistication, symbolism). Engineers and business people must better understand these factors to produce more successful products. Projects, papers, guest speakers, field trips.

3-4 units, Win (Beach, D)

ME 315. The Designer in Society

For graduate students. Career objectives and psychological orientation compared with existing social values and conditions. Emphasis is on assisting individuals in assessing their roles in society. Readings on political, social, and humanistic thought are related to technology and design. Experiential, in-class exercises, and term project. Enrollment limited to 24.

3 units, Spr (Roth, B)

ME 316A. Product Design Master's Project

For graduate Product Design or Design (Art) majors only. Students create and present two master's theses under the supervision of engineering and art faculty. Theses involve the synthesis of aesthetics and technological concerns in the service of human need and possibility. Product Design students register for 4 units; Art students for 2 units. Prerequisites: ME 216B, ME 365 Corequisite: ARTSTUDI 360.

2-4 units, Aut (Banerjee, S; Burnett, W; Kelley, D; Barry, M)

ME 316B. Product Design Master's Project

Continuation of 316A.

2-4 units, Win (Banerjee, S; Burnett, W; Barry, M; Kelley, D)

ME 316C. Product Design Master's Project

Continuation of 316B.

2-4 units, Spr (Banerjee, S; Burnett, W; Kelley, D; Barry, M)

ME 317A. Design for Manufacturability: Product Definition for Market Success

Systematic methodologies to define, develop, and produce world-class products. Student team projects to identify opportunities for improvement and develop a comprehensive product definition. Topics include value engineering, quality function deployment, design for assembly and producibility, design for variety and supply chain, design for life-cycle quality, and concurrent engineering. Students must take 317B to complete the project and obtain a letter grade. On-campus enrollment limited to 20; SCPD class size limited to 50, and each site must have at least 3 students to form a project team.

4 units, Win (Ishii, K)

ME 317B. Design for Manufacturability: Quality by Design for Customer Value

Building on 317A, focus is on the implementation of competitive product design. Student groups apply structured methods to optimize the design of an improved product, and plan for its manufacture, testing, and service. The project deliverable is a comprehensive product and process specification. Topics: concept generation and selection (Pugh's Method), FMEA applied to the manufacturing process, design for robustness, Taguchi Method, SPC and six sigma process, tolerance analysis, flexible manufacturing, product testing, rapid prototyping. Enrollment limited to 40, not including SCPD students. Minimum enrollment of two per SCPD viewing site; single student site by prior consent of instructor. On-campus class limited to 20. For SCPD students, limit is 50 and each site must have a minimum of three students to form a project team and define a project on their own. Prerequisite: 317A.

4 units, Spr (Ishii, K)

ME 318. Computer-Aided Product Creation

Design course focusing on an integrated suite of computer tools: rapid prototyping, solid modeling, computer-aided machining, and computer numerical control manufacturing. Students choose, design, and manufacture individual products, emphasizing individual design process and computer design tools. Field trips demonstrate Stanford Product Realization Lab's relationship to the outside world. Structured lab experiences build a basic CAD/CAM/CNC proficiency. Limited enrollment. Prerequisite: consent of instructor.

4 units, Aut (Staff), Win (Staff), Spr (Staff)

ME 322. Kinematic Synthesis of Mechanisms

The rational design of linkages. Techniques to determine linkage proportions to fulfill design requirements using analytical, graphical, and computer based methods.

3 units, Win (Roth, B)

ME 323. Modeling and Identification of Mechanical Systems for Control

Lecture/Lab. The art and science behind developing mathematical models for control system design. Theoretical and practical system modeling and parameter identification. Frequency domain identification, parametric modeling, and black-box identification. Analytical work and laboratory experience with identification, controller implementation, and the implications of unmodeled dynamics and non-linearities. Prerequisites: linear algebra and system simulation with MATLAB/SIMULINK; ENGR 105.

3 units, Aut (Gerdes, C)

ME 324. Precision Engineering

Advances in engineering are often enabled by more accurate control of manufacturing and measuring tolerances. Concepts and technology enable precision such that the ratio of overall dimensions to uncertainty of measurement is large relative to normal engineering practice. Typical application areas: non-spherical optics, computer information storage devices, and manufacturing metrology systems. Application experience through design and manufacture of a precision engineering project, emphasizing the principles of precision engineering. Structured labs; field trips. Prerequisite: consent of instructors.

4 units, Spr (Beach, D; DeBra, D)

ME 326. Telerobotics and Human-Robot Interactions

Focus is on dynamics and controls. Evaluation and implementation of required control systems. Topics include master-slave systems, kinematic and dynamic similarity; control architecture, force feedback, haptics, sensory substitutions; stability, passivity, sensor resolution, servo rates; time delays, prediction, wave variables. Hardware-based projects encouraged, which may complement ongoing research or inspire new developments. Limited enrollment. Prerequisites: ENGR 205, 320 or CS 223A, or consent of instructor. (Niemeyer)

3 units, not given this year

ME 329. Physical Solid Mechanics

Quantum mechanics, statistical mechanics, and solid state physics for engineering students. The theory describes physical processes at nanoscale in solid materials. Atomic structures of solids and their electronic structures. Statistical mechanics provides a theoretical framework for thermodynamics to connect the nanoscale processes to macroscopic properties of solids.

3 units, alternate years, not given this year

ME 330. Advanced Kinematics

Kinematics from mathematical viewpoints. Introduction to algebraic geometry of point, line, and plane elements. Emphasis is on basic theories which have potential application to mechanical linkages, computational geometry, and robotics.

3 units, Aut (Roth, B)

ME 331A. Classical Dynamics

(Same as AA 242A.) Accelerating and rotating reference frames. Kinematics of rigid body motion; Euler angles, direction cosines. D'Alembert's principle, equations of motion. Inertia properties of rigid bodies. Dynamics of coupled rigid bodies. Lagrange's equations and their use. Dynamic behavior, stability, and small departures from equilibrium. Prerequisite: ENGR 15 or equivalent.

3 units, Win (Mitiguy, P)

ME 331B. Advanced Dynamics

(Same as AA 242B.) Formulation of equations of motion with Newton/Euler equations; angular momentum principle; D'Alembert principle; power, work, and energy; Kane's method; and Lagrange's equations. Numerical solutions of nonlinear algebraic and dfferential equations govering the behavior of multiple degree of freedom systems. Computed torque control.

3 units, Spr (Mitiguy, P)

ME 333. Mechanics

Goal is a common basis for advanced mechanics courses. Formulation of the governing equations from a Lagrangian perspective. Examples include systems of particles and linear elastic solids. Waves in discrete and continuous media. Linear elasticity formulation in the static and dynamic cases, and elementary measures of stress and strain. Tensor and variational calculus. (Lew)

3 units, Aut (Lew, A)

ME 335A. Finite Element Analysis

Fundamental concepts and techniques of primal finite element methods. Method of weighted residuals, Galerkin's method, and variational equations. Linear elliptic boundary value problems in one, two, and three space dimensions; applications in structural, solid, and fluid mechanics and heat transfer. Properties of standard element families and numerically integrated elements. Implementation of the finite element method. Active column equation solver, assembly of equations, and element routines. The mathematical theory of finite elements.

3 units, Aut (Pinsky, P)

ME 335B. Finite Element Analysis

Finite element methods for linear dynamic analysis. Eigenvalue, parabolic, and hyperbolic problems. Mathematical properties of semi-discrete (t-continuous) Galerkin approximations. Modal decomposition and direct spectral truncation techniques. Stability, consistency, convergence, and accuracy of ordinary differential equation solvers. Asymptotic stability, over-shoot, and conservation laws for discrete algorithms. Mass reduction. Applications in heat conduction, structural vibrations, and elastic wave propagation. Computer implementation of finite element methods in linear dynamics. Implicit, explicit, and implicit-explicit algorithms and code architectures.

3 units, Win (Pinsky, P)

ME 335C. Introduction to Boundary Element Analysis

The boundary integral equation and boundary element method with applications to potential theory and elastostatics. Green's function methods for transforming partial differential equations to integral equations with boundary conditions built in. Implementation of the method and treatments of weakly and strongly (Cauchy principal values) singular kernels. Coupling with finite element methods. Additional topics may include fracture mechanics, contact mechanics, and transient diffusion.

3 units, Spr (Pinsky, P)

ME 336. Crystalline Anisotropy

(Same as MATSCI 359.) Matrix and tensor analysis with applications to the effects of crystal symmetry on elastic deformation, thermal expansion, diffusion, piezoelectricity, magnetism, thermodynamics, and optical properties of solids, on the level of J. F. Nye's Physical Properties of Crystals. Homework sets use Mathematica.

3 units, Win (Barnett, D)

ME 337. Mechanics of Growth

Introdution to continuum theory and numerical solutions or biomechanical problems. Kinematics of finite growth. Balance equations in open system thermodynamics. Constitutive equations for biological tissues. Enhanced finite element models in biomechanics. Analytical solutions for simple model problems. Numerical solutions for more advanced problems such as: bone remodeling; wound healing; muscle regeneration; tumor growth; atherosclerosis; in-stent restenosis; and tissue engineering.

3 units, not given this year

ME 338A. Continuum Mechanics

Nonlinear continuum mechanics for solids and fluids. Kinematics of finite deformations. Measures of strain and stress. Finite rotations. Linearized kinematics and infinitesimal measures of deformations. Rates. Conservation laws for mass, momenta, and energy. Boundary value problem in continuum mechanics. Prerequisites: 333 and 300, or equivalent background with consent of instructor.

3 units, Win (Kuhl, E)

ME 339. Mechanics of the Cell

Kinematical description of basic structural elements used to model parts of the cell: rods, ropes, membranes, and shells. Formulation of constitutive equations: nonlinear elasticity and entropic contributions. Elasticity of polymeric networks. Applications to model basic filaments of the cytoskeleton: actin, microtubules, intermediate filaments, and complete networks. Applications to biological membranes. (Jacobs)

3 units, Aut (Kuhl, E)

ME 340A. Theory and Applications of Elasticity

Elasticity theory and application to material structures at microscale. Theories: stress, strain, and energy; equilibrium and compatibility conditions; boundary value problem. Solution methods: stress function, Green's function, Fourier transformation. Numerical exercises using Matlab. Applications to defects in solids, thin films, and biomembranes.

3 units, Spr (Cai, W)

ME 340B. Elasticity in Microscopic Structures

Elasticity theory and applications to structures in micro devices, material defects, and biological systems. Theoretical basis: stress, strain, and energy; equilibrium and compatibility conditions; boundary value problem formulation. Solution methods: stress function, Green's function, and Fourier transformation; moderate numerical exercises using Matlab. Methods and solutions applied to the elastic behaviors of thin films and MEMS structures, cracks and dislocations, and cell filaments and membranes.

3 units, not given this year

ME 341. Biomechanics of Hearing, Speech, and Balance

Theory and practice of building mathematical models to understand physical phenomena; integration of imaging, physiology, and biomechanics. Journal club style discussions of research literature, examples from hearing science, speech production, and the vestibular system. Dualisms in modeling include: general principles versus detailed models; analytic versus computational models; forward versus inverse approaches; and the interplay between theory and experiments.

3 units, alternate years, not given this year

ME 342A. MEMS Laboratory

Practice and theory of MEMS device design and fabrication, orientation to fabrication facilities, and introduction to techniques for design and evaluation of MEMS devices in the context of designed projects. Emphasis on MEMS design (need finding, brainstorming, evaluation, and design methodology), characterization, and fabrication, including photolithography, etching, oxidation, diffusion, and ion implanation. Limited enrollment. Prerequisite: engineering or science background and consent of instructor.

3-4 units, not given this year

ME 342D. MEMS Laboratory Assignments

Prerequisite: consent of instructor.

1-2 units, not given this year

ME 343. An Introduction to Waves in Elastic Solids

One-dimensional motion of an elastic continuum, the linearized theory of elasticity and elastodynamic theory, elastic waves in an unbounded medium, plane harmonic waves in elastic half-spaces including reflection and refraction, slowness, energy velocity and anisotropic effects. Text is first five chapters of Achenbach's Wave Propagation in Elastic Solids. (Barnett)

3 units, not given this year

ME 344A. Computational Nanotechnology

Atomistic simulations as computational tools to design nanoscale materials and devices. Nanoparticles and nanowires introduced as main classes of nano building blocks. Computational modeling of carbon nanomaterials (fullerenes and nanotubes); nanoparticles and quantum dots; semiconductor and metal nanowires; and molecular wires. Atomistic modeling programs with graphical user interface used to gain hands-on experience of nanomaterials design.

3 units, not given this year

ME 344B. Nanomaterials Modeling

Atomistic and quantum mechanical simulation methods. Focus is quantum simulation of nanomaterials. Review of concepts and practical techniques of atomistic simulations; finite difference algorithms and practical computational issues for molecular dynamics and Monte Carlo simulations. Graphical user interface, designing nanomaterials through analysis and feedback processes, configuration optimization, dynamic mode analysis, and electronic structure analysis. Hands-on experience in computational design of nanomaterials, and fundamentals of simulations.

3 units, not given this year

ME 345. Fatigue Design and Analysis

The mechanism and occurrences of fatigue in service. Methods for predicting fatigue life and for protecting against premature fatigue failure. Use of elastic stress and inelastic strain analyses to predict crack initiation life. Use of linear elastic fracture mechanics to predict crack propagation life. Effects of stress concentrations, manufacturing processes, load sequence, irregular loading, multi-axial loading. Subject is treated from the viewpoints of the engineer seeking up-to-date methods of life prediction and the researcher interested in improving understanding of fatigue behavior. Prerequisite: undergraduate mechanics of materials.

3 units, not given this year

ME 346A. Introduction to Statistical Mechanics

Concepts and tools of classical statistical mechanics and applications to molecular systems. Thermodynamics and probability theory. Statistical ensembles. Information and entropy. Free energy and transition between metastable states. Brownian motion, Langevin dynamics, and Fokker-Planck equation. Non-equilibrium systems: correlation and response functions, fluctuation-dissipation theorem. Applications to self-assembly, thin film growth, and structural transformation.

3 units, Win (Staff)

ME 346B. Introduction to Molecular Simulations

Algorithms of molecular simulations and underlying theories. Molecular dynamics, time integrators, modeling thermodynamic ensembles (NPT, NVT), free energy, constraints. Monte Carlo simulations, parallel tempering. Stochastic equations, Langevin and Brownian dynamics. Applications in solids, liquids, and biomolecules (proteins). Programming in Matlab and C++. Prerequisites: ME 346A or equivalent, Matlab, and C++.

3 units, Spr (Darve, E)

ME 346C. Advanced Techniques for Molecular Simulations

Advanced methods for computer simulation of proteins. Symplectic time integrators, multiple-time stepping, energy conservation. Long-range force calculation, particle mesh Ewald, fast multipole method, multigrid. Free energy methods, umbrella sampling, acceptance ratio, thermodynamic integration, non equilibrium methods, adaptive biasing force. Prerequisites: ME 346A,B or equivalent, Matlab, and C++.

3 units, alternate years, not given this year

ME 347. Mathematical Theory of Dislocations

The mathematical theory of straight and curvilinear dislocations in linear elastic solids. Stress fields, energies, and Peach-Koehler forces associated with these line imperfections. Anisotropic effects, Green's function methods, and the geometrical techniques of Brown and Indenborn-Orlov for computing dislocation fields and for studying dislocation interactions. Continuously distributed dislocations and cracks and inclusions.

3 units, not given this year

ME 348. Experimental Stress Analysis

Theory and applications of photoelasticity, strain gages, and holographic interferometry. Comparison of test results with theoretical predictions of stress and strain. Other methods of stress and strain determination (optical fiber strain sensors, thermoelasticity, Moire, residual stress determination).

3 units, not given this year

ME 351A. Fluid Mechanics

Exact and approximate analysis of fluid flow covering kinematics, global and differential equations of mass, momentum, and energy conservation. Forces and stresses in fluids. Euler's equations and the Bernoulli theorem applied to inviscid flows. Vorticity dynamics. Topics in irrotational flow: stream function and velocity potential for exact and approximate solutions; superposition of solutions; complex potential function; circulation and lift. Some boundary layer concepts.

3 units, Aut (Iaccarino, G)

ME 351B. Fluid Mechanics

Laminar viscous fluid flow. Governing equations, boundary conditions, and constitutive laws. Exact solutions for parallel flows. Creeping flow limit, lubrication theory, and boundary layer theory including free-shear layers and approximate methods of solution; boundary layer separation. Introduction to stability theory and transition to turbulence, and turbulent boundary layers. Prerequisite: 351A.

3 units, Win (Eaton, J)

ME 352A. Radiative Heat Transfer

The fundamentals of thermal radiation heat transfer; blackbody radiation laws; radiative properties of non-black surfaces; analysis of radiative exchange between surfaces and in enclosures; combined radiation, conduction, and convection; radiative transfer in absorbing, emitting, and scattering media. Advanced material for students with interests in heat transfer, as applied in high-temperature energy conversion systems. Take 352B,C for depth in heat transfer. Prerequisites: graduate standing and undergraduate course in heat transfer. Recommended: computer skills.

3 units, Aut (Mitchell, R)

ME 352B. Fundamentals of Heat Conduction

Physical description of heat conduction in solids, liquids, and gases. The heat diffusion equation and its solution using analytical and numerical techniques. Data and microscopic models for the thermal conductivity of solids, liquids, and gases, and for the thermal resistance at solid-solid and solid-liquid boundaries. Introduction to the kinetic theory of heat transport, focusing on applications for composite materials, semiconductor devices, micromachined sensors and actuators, and rarefied gases. Prerequisite: consent of instructor.

3 units, Win (Goodson, K)

ME 352C. Convective Heat Transfer

Prediction of heat and mass transfer rates based on analytical and numerical solutions of the governing partial differential equations. Heat transfer in fully developed pipe and channel flow, pipe entrance flow, laminar boundary layers, and turbulent boundary layers. Superposition methods for handling non-uniform wall boundary conditions. Approximate models for turbulent flows. Comparison of exact and approximate analyses to modern experimental results. General introduction to heat transfer in complex flows. Prerequisite: 351B or equivalent.

3 units, Spr (Eaton, J)

ME 354. Experimental Methods in Fluid Mechanics

Experimental methods associated with the interfacing of laboratory instruments, experimental control, sampling strategies, data analysis, and introductory image processing. Instrumentation including point-wise anemometers and particle image tracking systems. Lab. Prerequisites: previous experience with computer programming and consent of instructor. Limited enrollment.

4 units, not given this year

ME 355. Compressible Flow

Topics include quasi-one-dimensional isentropic flow in variable area ducts, normal shock waves, oblique shock and expansion waves, flow in ducts with friction and heat transfer, unsteady one-dimensional flow, and steady two-dimensional supersonic flow.

3 units, Spr (Bowman, C)

ME 357. Turbine and Internal Combustion Engines

(Same as ME 257.) Principles of design analysis for aircraft gas turbines and automotive piston engines. Analysis for aircraft engines performed for Airbus A380 type aircraft. Design parameters determined considering aircraft aerodynamics, gas turbine thermodynamics, compressible flow physics, and material limitations. Additional topics include characteristics of main engine components, off-design analysis, and component matching. Performance of automotive piston engines including novel engine concepts in terms of engine thermodynamics, intake and exhaust flows, and in-cylinder flow.

3 units, Win (Pitsch, H)

ME 358. Heat Transfer in Microdevices

Application-driven introduction to the thermal design of electronic circuits, sensors, and actuators that have dimensions comparable to or smaller than one micrometer. The impact of thin-layer boundaries on thermal conduction and radiation. Convection in microchannels and microscopic heat pipes. Thermal property measurements for microdevices. Emphasis is on Si and GaAs semiconductor devices and layers of unusual, technically-promising materials such as chemical-vapor-deposited (CVD) diamond. Final project based on student research interests. Prerequisite: consent of instructor.

3 units, Spr (Asheghi, M)

ME 359A. Advanced Design and Engineering of Space Systems I

The application of advanced theory and concepts to the development of spacecraft and missile subsystems; taught by experts in their fields. Practical aspects of design and integration. Mission analysis, systems design and verification, radiation and space environments, orbital mechanics, space propulsion, electrical power and avionics subsystems, payload communications, and attitude control. Subsystem-oriented design problems focused around a mission to be completed in groups. Tours of Lockheed Martin facilities. Limited enrollment. Prerequisites: undergraduate degree in related engineering field or consent of instructor.

4 units, not given this year

ME 359B. Advanced Design and Engineering of Space Systems II

Continuation of 359A. Topics include aerospace materials, mechanical environments, structural analysis and design, finite element analysis, mechanisms, thermal control, probability and statistics. Tours of Lockheed Martin facilities. Limited enrollment. Prerequisites: undergraduate degree in related field, or consent of instructor.

4 units, not given this year

ME 361. Turbulence

Governing equations. Averaging and correlations. Reynolds equations and Reynolds stresses. Free shear flows, turbulent jet, turbulent length and time scales, turbulent kinetic energy and kinetic energy dissipation, and kinetic energy budget. Kolmogorov's hypothesis and energy spectrum. Wall bounded flows, channel flow and boundary layer, viscous scales, and law of the wall. Turbulence modeling, gradient transport and eddy viscosity, mixing length model, two-equation models, Reynolds-stress model, and large-eddy simulation.

3 units, Spr (Pitsch, H)

ME 362A. Physical Gas Dynamics

Concepts and techniques for description of high-temperature and chemically reacting gases from a molecular point of view. Introductory kinetic theory, chemical thermodynamics, and statistical mechanics as applied to properties of gases and gas mixtures. Transport and thermodynamic properties, law of mass action, and equilibrium chemical composition. Maxwellian and Boltzmann distributions of velocity and molecular energy. Examples and applications from areas of current interest such as combustion and materials processing.

3 units, Aut (Cappelli, M)

ME 362B. Nonequilibrium Processes in High-Temperature Gases

Chemical kinetics and energy transfer in high-temperature gases. Collision theory, transition state theory, and unimolecular reaction theory. Prerequisie: 362A or consent of instructor.

3 units, Win (Hanson, R)

ME 363. Partially Ionized Plasmas and Gas Discharges

Introduction to partially ionized gases and the nature of gas discharges. Topics: the fundamentals of plasma physics emphasizing collisional and radiative processes, electron and ion transport, ohmic dissipation, oscillations and waves, interaction of electromagnetic waves with plasmas. Applications: plasma diagnostics, plasma propulsion and materials processing. Prerequisite: 362A or consent of instructor.

3 units, Spr (Cappelli, M)

ME 364. Optical Diagnostics and Spectroscopy

The spectroscopy of gases and laser-based diagnostic techniques for measurements of species concentrations, temperature, density, and other flow field properties. Topics: electronic, vibrational, and rotational transitions; spectral lineshapes and broadening mechanisms; absorption, fluorescence, Rayleigh and Raman scattering methods; collisional quenching. Prerequisite: 362A or equivalent.

3 units, not given this year

ME 365. The Structure of Design Research

Restricted to second-year Joint Program in Design graduate students; prerequisite for ME 316A,B,C. How to shape individual research plans, identify tools for design research, and develop a vocabulary for research through design. Students present proposals for master's theses. Case studies.

1-3 units, Spr (Banerjee, S)

ME 367. Optical Diagnostics and Spectroscopy Laboratory

Principles, procedures, and instrumentation associated with optical measurements in gases and plasmas. Absorption, fluorescence and emission, and light-scattering methods. Measurements of temperature, species concentration, and molecular properties. Lab. Enrollment limited to 16. Prerequisite: 362A or 364.

4 units, Spr (Hanson, R)

ME 368A. Biodesign Innovation: Needs Finding and Concept Creation

(Same as BIOE 374A, MED 272A, OIT 581.) Two quarter sequence. Inventing new medical devices and instrumentation, including: methods of validating medical needs; techniques for analyzing intellectual property; basics of regulatory (FDA) and reimbursement planning; brainstorming and early prototyping. Guest lecturers and practical demonstrations.

2 units, Win (Yock, P; Zenios, S; Brinton, T; Milroy, C)

ME 368B. Biodesign Innovation: Concept Development and Implementation

(Same as BIOE 374B, MED 272B, OIT 583.) Two quarter sequence. How to take a medical device invention forward from early concept to technology translation and development. Topics include prototyping; patent strategies; advanced planning for reimbursement and FDA approval; choosing translation route (licensing versus start-up); ethical issues including conflict of interest; fundraising approaches and cash requirements; essentials of writing a business or research plan; strategies for assembling a development team.

2 units, Spr (Yock, P; Zenios, S; Brinton, T; Milroy, C)

ME 369A. Biodesign Innovation, Project A

(Same as BIOE 375A, MED 273A, OIT 582.) Interdisciplinary student teams select a medical need, characterize it fully, develop a needs statement, invent potential conceptual approaches to solving the need, and pursue initial prototyping and planning for regulatory and reimbursement pathways. Guest experts. Corequisite: MED 272A/BIOE 374A/ME 368A/OIT 581.

2 units, Win (Yock, P; Zenios, S; Milroy, C; Brinton, T)

ME 369B. Biodesign Innovation, Project B

(Same as BIOE 375B, MED 273B, OIT 584.) Interdisciplinary teams select the most promising invention from BIOE 375A and move into prototyping and project planning. Teams develop strategies for patenting, FDA submission, third-party reimbursement, licensing agreement or launching a start-up, including cash forecasting and business plan. Prerequisites: MED 375A/ME 369A/BIOE 375A/OIT 582. Corequisite: MED 272B/ME 368B/BIOE 374B/OIT 583.

2 units, Spr (Yock, P; Milroy, J; Brinton, T; Zenios, S)

ME 370A. Energy Systems I: Thermodynamics

Thermodynamic analysis of energy systems emphasizing systematic methodology for and application of basic principles to generate quantitative understanding. Availability, mixtures, reacting systems, phase equilibrium, chemical availability, and modern computational methods for analysis. Prerequisites: undergraduate engineering thermodynamics and computer skills such as Matlab.

3 units, Aut (Bowman, C)

ME 370B. Energy Systems II: Modeling and Advanced Concepts

Development of quantitative device models for complex energy systems, including fuel cells, reformers, combustion engines, and electrolyzers, using thermodynamic and transport analysis. Student groups work on energy systems to develop conceptual understanding, and high-level, quantitative and refined models. Advanced topics in thermodynamics and special topics associated with devices under study. Prerequisite: 370A.

4 units, Win (Edwards, C)

ME 370C. Energy Systems III: Projects

Refinement and calibration of energy system models generated in ME 370B carrying the models to maturity and completion. Integration of device models into a larger model of energy systems. Prerequisites: 370A,B, consent of instructor.

4 units, Spr (Edwards, C)

ME 371. Combustion Fundamentals

Heat of reaction, adiabatic flame temperature, and chemical composition of products of combustion; kinetics of combustion and pollutant formation reactions; conservation equations for multi-component reacting flows; propagation of laminar premixed flames and detonations. Prerequisite: 362A or 370A, or consent of instructor.

3 units, Win (Zheng, X)

ME 372. Combustion Applications

The role of chemical and physical processes in combustion; ignition, flammability, and quenching of combustible gas mixtures; premixed turbulent flames; laminar and turbulent diffusion flames; combustion of fuel droplets and sprays. Prerequisite: 371.

3 units, Spr (Zheng, X)

ME 377. Experiences in Innovation and Design Thinking

Lecture/lab. Immersive experiences in innovation and design thinking, blurring the boundaries among technology, business, and human values. Tenets of design thinking including being human-centered, prototype-driven, and mindful of process. Topics include design processes, innovation methodologies, need finding, human factors, rapid prototyping, team dynamics, storytelling, and project management. Hands-on projects, in-class exercises, and guest lectures. Students and faculty from areas including business, earth sciences, education, engineering, humanities and sciences, law, and medicine. Preparation for advanced d.school courses. Limited enrollment. Application required. See http://dschool.stanford.edu/projects/classes/me377.html.

3-4 units, Aut (Kembel, G), Win (Kembel, G), Spr (Kembel, G)

ME 377A. Experiences in Innovation and Design Thinking

Design processes, innovation methodologies, need finding, human factors, rapid prototyping, team dynamics, storytelling, and project management. Preparation for real-world innovation and other d.school projects. Hands-on exercises and team projects focusing on process, frameworks, and methods.

2-3 units, not given this year

ME 377B. Experiences in Innovation and Design Thinking

Design processes, innovation methodologies, need finding, human factors, rapid prototyping, team dynamics, storytelling, and project management. Preparation for real-world innovation and other d.school projects. Hands-on exercises and team projects focusing on process, frameworks, and methods.

2-3 units, not given this year

ME 377C. Experiences in Innovation and Design Thinking

Design processes, innovation methodologies, need finding, human factors, rapid prototyping, team dynamics, storytelling, and project management. Preparation for real-world innovation and other d.school projects. Hands-on exercises and team projects focusing on process, frameworks, and methods.

2-3 units, not given this year

ME 381. Orthopaedic Bioengineering

Engineering approaches applied to the musculoskeletal system in the context of surgical and medical care. Fundamental anatomy and physiology. Material and structural characteristics of hard and soft connective tissues and organ systems, and the role of mechanics in normal development and pathogenesis. Engineering methods used in the evaluation and planning of orthopaedic procedures, surgery, and devices.

3 units, not given this year

ME 382A. Medical Device Design

Real world problems and challenges of biomedical device design and evaluation. Students engage in industry sponsored projects resulting in new designs, physical prototypes, design analyses, computational models, and experimental tests, gaining experience in: the formation of design teams; interdisciplinary communication skills; regulatory issues; biological, anatomical, and physiological considerations; testing standards for medical devices; and intellectual property.

4 units, Win (Andriacchi, T)

ME 382B. Medical Device Design

Continuation of industry sponsored projects from 382A. With the assistance of faculty and expert consultants, students finalize product designs or complete detailed design evaluations of new medical products. Bioethics issues and strtegies for funding new medical ventures.

4 units, Spr (Andriacchi, T)

ME 385. Tissue Engineering Lab

Hands-on experience in the fabrication of living engineered tissues. Techniques include sterile technique, culture of mammalian cells, creation of cell-seeded scaffolds, and the effects of mechanical loading on the metabolism of living engineered tissues. Theory, background, and practical demonstration for each technique. Lab.

1-2 units, not given this year

ME 386. Neuromuscular Biomechanics

(Same as BIOE 386.) The interplay between mechanics and neural control of movement. State of the art assessment through a review of classic and recent journal articles. Emphasis is on the application of dynamics and control to the design of assistive technology for persons with movement disorders.

3 units, not given this year

ME 390. Thermosciences Research Project Seminar

Review of work in a particular research program and presentations of other related work.

1 unit, not given this year

ME 391. Engineering Problems

Directed study for graduate engineering students on subjects of mutual interest to student and staff member. May be used to prepare for experimental research during a later quarter under 392. Faculty sponsor required.

1-5 units, Aut (Staff), Win (Staff), Spr (Staff), Sum (Staff)

ME 392. Experimental Investigation of Engineering Problems

Graduate engineering students undertake experimental investigation under guidance of staff member. Previous work under 391 may be required to provide background for experimental program. Faculty sponsor required.

1-5 units, Aut (Staff), Win (Staff), Spr (Staff), Sum (Staff)

ME 393. Topics in Biologically Inspired or Human Interactive Robotics

Application of observations from human and animal physiology to robotic systems. Force control of motion including manipulation, haptics, and locomotion. Weekly literature review forum led by student. May be repeated for credit. (Cutkosky, Waldron, Niemeyer)

1 unit, Aut (Staff)

ME 394. Design Forum

Introduction to the design faculty and research labs. Faculty describe their work and research interests followed by open discussion.

1 unit, not given this year

ME 395. Seminar in Solid Mechanics

Required of Ph.D. candidates in solid mechanics. Guest speakers present research topics related to mechanics theory, computational methods, and applications in science and engineering. May be repeated for credit. See http://mc.stanford.edu.

1 unit, Aut (Pruitt, B), Win (Pruitt, B; Kuhl, E), Spr (Kuhl, E)

ME 396. Design and Manufacturing Forum

(Same as ME 196.) Guest speakers address issues of interest to design and manufacturing engineers. Sponsored by Stanford Engineering Club for Automation and Manufacturing (SECAM). May be repeated for credit

1 unit, Win (Reis, R), Spr (Reis, R)

ME 397. Design Theory and Methodology Seminar

What do designers do when they do design? How can their performance be improved? Topics change each quarter. May be repeated for credit.

1-3 units, Aut (Leifer, L; Mabogunje, A; Sonalkar, N), Win (Leifer, L; Mabogunje, A), Spr (Leifer, L; Mabogunje, A)

ME 398. Biomechanical Research Symposium

Guest speakers present contemporary research on experimental and theoretical aspects of biomechanical engineering and bioengineering. May be repeated for credit.

1 unit, Aut (Levenston, M), Win (Levenston, M), Spr (Levenston, M)

ME 399. Fuel Cell Seminar

Interdisciplinary research in engineering, chemistry, and physics. Talks on fundamentals of fuel cells by speakers from Stanford, other academic and research institutions, and industry. The potential to provide high efficiency and zero emissions energy conversion for transportation and electrical power generation.

1 unit, not given this year

ME 400. Thesis (Engineer Degree)

Investigation of some engineering problems. Required of Engineer degree candidates

2-15 units, Aut (Staff), Win (Staff), Spr (Staff), Sum (Staff)

ME 405. Asymptotic Methods and Applications

Asymptotic versus convergent expansions, approximation of integrals, method of matched asymptotics, WKB method and turning points, method of multiple scales. Applications: viscous and potential flow, wave propagation, combustion, and electrostatics. Prerequisites: ME 300B, graduate-level fluid mechanics.

3 units, not given this year

ME 406. Turbulence Physics and Modeling Using Numerical Simulation Data

Prerequisite: consent of instructor.

2 units, Sum (Moin, P)

ME 408. Spectral Methods in Computational Physics

Data analysis, spectra and correlations, sampling theorem, nonperiodic data, and windowing; spectral methods for numerical solution of ordinary and partial differential equations; accuracy and computational cost; fast Fourier transform, Galerkin, collocation, and Tau methods; spectral and pseudospectral methods based on Fourier series and eigenfunctions of singular Sturm-Liouville problems; Chebyshev, Legendre, and Laguerre representations; convergence of eigenfunction expansions; discontinuities and Gibbs phenomenon; aliasing errors and control; efficient implementation of spectral methods; spectral methods for complicated domains; time differencing and numerical stability.

3 units, Win (Moin, P)

ME 410A. Foresight and Innovation

The art, science, and practice of design innovation. Tools such as critical foresight and anticipatory research design thinking that assist organizations in improving the quality and speed of research and design innovation programs. The path from idea to market. How to communicate a developing idea through scenarios, business pitches, and product prototypes. Prerequisite: consent of instructor.

1-5 units, Aut (Leifer, L; Cockayne, W)

ME 410B. Foresight and Innovation

The art, science, and practice of design innovation. Tools such as critical foresight and anticipatory research that assist organizations in improving the quality and speed of research and design innovation programs. The path from idea to market. How to communicate a developing idea through scenarios, business pitches, and product prototypes.

1-5 units, Win (Leifer, L; Cockayne, W)

ME 410C. Foresight and Innovation

The art, science, and practice of design innovation. Tools such as critical foresight and anticipatory research that assist organizations in improving the quality and speed of research and design innovation programs. The path from idea to market. How to communicate a developing idea through scenarios, business pitches, and product prototypes.

1-5 units, Spr (Leifer, L; Cockayne, W)

ME 410X. Foresight Project Experience with Corporate Partners

Participation in a global foresight research team with real-world industrial partners. Foresight and anticipatory research developed become part of the student's portfolio. May be repeated for credit. Limited enrollment. Prerequisite: consent of instructor.

1-5 units, Aut (Leifer, L; Cockayne, W), Win (Leifer, L; Cockayne, W), Spr (Leifer, L; Cockayne, W), Sum (Leifer, L; Cockayne, W)

ME 412. Engineering Functional Analysis and Finite Elements

(Same as CME 356.) Concepts in functional analysis to understand models and methods used in simulation and design. Topology, measure, and integration theory to introduce Sobolev spaces. Convergence analysis of finite elements for the generalized Poisson problem. Extensions to convection-diffusion-reaction equations and elasticity. Upwinding. Mixed methods and LBB conditions. Analysis of nonlinear and evolution problems. Prerequisites: 335A,B, CME 200, CME 204, or consent of instructor. Recommended: 333, MATH 171.

3 units, Win (Lew, A)

ME 413. Quantum Confinement Structures: Physics and Fabrication

Quantum mechanics principles and the thermodynamics of confinement structures. Focus is on potential applications such as solar cells and catalysis. Student presentations. Lab demonstrations. Prerequisite: background in quantum mechanics and statistical thermodynamics.

3 units, Spr (Prinz, F)

ME 414. Solid State Physics Issues for Mechanical Engineering Experiments

Principles of statistical mechanics, quantum mechanics, and solid-state physics. Provides graduate mechanical engineering students with understanding needed to work on devices or technologies which rely on solid-state physics.

3 units, Sum (Kenny, T)

ME 417. Total Product Integration Engineering

For students aspiring to be product development executives and leaders in research and education. Advanced methods and tools beyond the material covered in 217: quality design across global supply chain, robust product architecture for market variety and technology advances, product development risk management. Small teams or individuals conduct a practical project that produces a case study or enhancement to produce development methods and tools. Enrollment limited to 12. Prerequisites: 317A,B.

4 units, Aut (Ishii, K)

ME 420. Applied Electrochemistry: Micro- and Nanoscale

Concepts of physical chemistry such as thermodynamic equilibrium, reaction kinetics, and mass transport mechanisms from which the fundamentals of electrochemistry are derived. Theory of electrochemical methods for material analyses and modifications with emphasis on scaling behaviors. Electrochemical devices such as sensors, actuators, and probes for scanning microscopes, and their miniaturization concepts. Examples of these devices built, characterized, and applied in labs using technologies such as scanning probe techniques. Projects focus on current problems in biology, material science, microfabrication, and energy conversion.

3 units, not given this year

ME 421. Thought Leaders Seminar for European Entrepreneurship and Innovation

Real-world experiences and challenges in startups, corporations, universities, nonprofit research institutes, and government ministries and agencies. Speakers include entrepreneurs, leaders from global technology companies, university researchers, venture capitalists, legal experts, senior policy makers, and European guests. May be repeated for credit.

1 unit, Win (Leifer, L; Lee, B), Spr (Leifer, L; Lee, B)

ME 438. Computational Molecular Modeling Project

Project-based class. Topics for projects include parallel methods for molecular dynamics, multiple time stepping algorithms, free energy computation, molecular pathways analysis, long-time scale behavior of numerical integrators, and multigrid based fast electrostatic algorithms. Students can propose their own projects. Final report and oral presentation. May be repeated for credit.

3 units, Sum (Darve, E)

ME 450. Advances in Biotechnology

Guest academic and industrial speakers. Latest developments in fields such as bioenergy, green process technology, production of industrial chemicals from renewable resources, protein pharmaceutical production, industrial enzyme production, stem cell applications, medical diagnostics, and medical imaging. Biotechnology ethics, business and patenting issues, and entrepreneurship in biotechnology.

3 units, not given next year

ME 451A. Advanced Fluid Mechanics

Topics: kinematics (analysis of deformation, critical points and flow topology, Helmholtz decomposition); constitutive relations (viscous and visco-elastic flows, non-inertial frames); vortex dynamics; circulation theorems, vortex line stretching and rotation, vorticity generation mechanisms, vortex filaments and Biot-Savart formula, local induction approximation, impulse and kinetic energy of vortex systems, vorticity in rotating frame. Prerequisite: graduate courses in compressible and viscous flow.

3 units, not given this year

ME 451B. Advanced Fluid Mechanics

Waves in fluids: surface waves, internal waves, inertial and acoustic waves, dispersion and group velocity, wave trains, transport due to waves, propagation in slowly varying medium, wave steepening, solitons and solitary waves, shock waves. Instability of fluid motion: dynamical systems, bifurcations, Kelvin-Helmholtz instability, Rayleigh-Benard convection, energy method, global stability, linear stability of parallel flows, necessary and sufficient conditions for stability, viscosity as a destabilizing factor, convective and absolute instability. Focus is on flow instabilities. Prerequisites: graduate courses in compressible and viscous flow.

3 units, not given this year

ME 451C. Advanced Fluid Mechanics

Compressible flow: governing equations, Crocco-Vazsonyi's equations, creation and destruction of vorticity by compressibility effects, shock waves. Modal decomposition of compressible flow, linear and nonlinear modal interactions, interaction of turbulence with shock waves. Energetics of compressible turbulence, effects of compressibility on free-shear flows, turbulent boundary layers, Van Direst transformation, recovery temperature, and shock/boundary layer interaction. Strong Reynolds analogy, modeling compressible turbulent flows. Prerequisites: 355, 361A, or equivalents.

3 units, Aut (Lele, S)

ME 453A. Finite Element-Based Modeling and Simulation of Linear Fluid/Structure Interaction Problems

Basic physics behind many fluid/structure interaction phenomena. Finite element-based computational approaches for linear modeling and simulation in the frequency domain. Vibrations of elastic structures. Linearized equations of small movements of inviscid fluids. Sloshing modes. Hydroelastic vibrations. Acoustic cavity modes. Structural-acoustic vibrations. Applications to liquid containers and underwater signatures. Prerequisite: graduate course in the finite element method or consent of instructor.

3 units, not given this year

ME 453B. Computational Fluid Dynamics Based Modeling of Nonlinear Fluid/Structure Interaction Problems

Basic physics behind many high-speed flow/structure interaction phenomena. Modern computational approaches for nonlinear modeling and simulation in the time domain. Dynamic equilibrium of restrained and unrestrained elastic structures. Corotational formulation for large structural displacements and rotations. Arbitrary Lagrangian-Eulerian description of inviscid and viscous flows. Time-accurate CFD on moving and deforming grids. Discrete geometric conservation laws. Discretization of transmission conditions on non-matching discrete fluid/structure interfaces. Coupled fluid/mesh-motion/structure time integration schemes. Application to divergence, flutter, and buffeting. Prerequisites: graduate course in the finite element method, and in computational fluid dynamics.

3 units, not given this year

ME 455. Complex Fluids and Non-Newtonian Flows

Definition of a complex liquid and microrheology. Division of complex fluids into suspensions, solutions, and melts. Suspensions as colloidal and non-colloidal. Extra stress and relation to the stresslet. Suspension rheology including Brownian and non-Brownian fibers. Microhydrodynamics and the Fokker-Planck equation. Linear viscoelasticity and the weak flow limit. Polymer solutions including single mode (dumbbell) and multimode models. Nonlinear viscoelasticity. Intermolecular effects in nondilute solutions and melts and the concept of reptation. Prerequisites: low Reynolds number hydrodynamics or consent of instructor.

3 units, not given this year

ME 457. Fluid Flow in Microdevices

Physico-chemical hydrodynamics. Creeping flow, electric double layers, and electrochemical transport such as Nernst-Planck equation; hydrodynamics of solutions of charged and uncharged particles. Device applications include microsystems that perform capillary electrophoresis, drug dispension, and hybridization assays. Emphasis is on bioanalytical applications where electrophoresis, electro-osmosis, and diffusion are important. Prerequisite: consent of instructor.

3 units, Win (Santiago, J)

ME 458. Advanced Topics in Electrokinetics

Electrokinetic theory and electrokinetic separation assays. Electroneutrality approximation and weak electrolyte electrophoresis theory. Capillary zone electrophoresis, field amplified sample stacking, isoelectric focusing, and isotachophoresis. Introduction to general electrohydrodynamics (EHD) theory including the leaky dielectric concept, the Ohmic model formulation, and electrokinetic flow instabilities. Prerequisite: ME 457.

3-5 units, Spr (Santiago, J)

ME 461. Advanced Topics in Turbulence

Turbulence phenomenology; statistical description and the equations governing the mean flow; fluctuations and their energetics; turbulence closure problem, two-equation turbulence models, and second moment closures; non-local effect of pressure; rapid distortion analysis and effect of shear and compression on turbulence; effect of body forces on turbulent flows; buoyancy-generated turbulence; suppression of turbulence by stratification; turbulent flows of variable density; effect of rotation on homogeneous turbulence; turbulent flows with strong vortices. Prerequisites: 351B and 361A, or consent of instructor.

3 units, not given this year

ME 463. Advanced Topics in Plasma Science and Engineering

Research areas such as plasma diagnostics, plasma transport, waves and instabilities, and engineering applications.

3 units, not given this year

ME 468. Experimental Research in Advanced User Interfaces

(Same as COMM 168, COMM 268, COMM 368.) (Undergraduates register for 168; master's students for 268; doctoral students for 368.) Project-based course involves small groups designing and implementing an experiment concerning voice and agent user interfaces. Each group is involved in a different, publishable research project. May be repeated for credit. Prerequisite: consent of instructor.

1-5 units, Win (Nass, C), Spr (Nass, C)

ME 469A. Computational Methods in Fluid Mechanics

Finite volume methods on stuctured and unstructured grids. Advanced methods for the solution of systems of equations. ADI schemes, preconditioned conjugate gradient and generalized minimum residual algorithms, multigrid methods, and deferred-correction approaches. Projection, fractional step, and artificial compressibility methods. Turbulent flows: direct numerical simulation, large eddy simulation, and Reynolds-averaged Navier-Stokes methods. Prerequisite: ME 300C/CME 206 or equivalent.

3 units, Win (Iaccarino, G)

ME 469B. Computational Methods in Fluid Mechanics

Advanced CFD codes. Geometry modeling, CAD-CFD conversion. Structured and unstructured mesh generation. Solution methods for steady and unsteady incompressible Navier-Stokes equations. Turbulence modeling. Conjugate (solid/fluid) heat transfer problems. Development of customized physical models. Batch execution for parametric studies. Final project involving solution of a problem of student's choosing. Prerequisite: ME 300C/CME 206.

3 units, not given this year

ME 470. Uncertainty Quantification

Uncertainty analysis in computational science. Probabilistic data representation, propagation techniques and validation under uncertainty. Mathematical and statistical foundations of random variables and processes for uncertainty modeling. Focus is on state-of-the-art propagation schemes, sampling techniques, and stochastic Galerkin methods. The concept of model validation under uncertainty and the determination of confidence bounds estimates. Prerequisite: basic probability and statistics at the level of CME 106 or equivalent.

3 units, Spr (Iaccarino, G)

ME 471. Turbulent Combustion

Basis of turbulent combustion models. Assumption of scale separation between turbulence and combustion, resulting in Reynolds number independence of combustion models. Level-set approach for premixed combustion. Different regimes of premixed turbulent combustion with either kinematic or diffusive flow/chemistry interaction leading to different scaling laws and unified expression for turbulent velocity in both regimes. Models for non-premixed turbulent combustion based on mixture fraction concept. Analytical predictions for flame length of turbulent jets and NOx formation. Partially premixed combustion. Analytical scaling for lift-off heights of lifted diffusion.

3 units, Aut (Pitsch, H)

ME 484. Computational Methods in Cardiovascular Bioengineering

(Same as BIOE 484.) Lumped parameter, one-dimensional nonlinear and linear wave propagation, and three-dimensional modeling techniques applied to simulate blood flow in the cardiovascular system and evaluate the performance of cardiovascular devices. Construction of anatomic models and extraction of physiologic quantities from medical imaging data. Problems in blood flow within the context of disease research, device design, and surgical planning.

3 units, Spr (Figueroa Alvarez, C)

ME 485. Modeling and Simulation of Human Movement

(Same as BIOE 485.) Direct experience with the computational tools used to create simulations of human movement. Lecture/labs on animation of movement; kinematic models of joints; forward dynamic simulation; computational models of muscles, tendons, and ligaments; creation of models from medical images; control of dynamic simulations; collision detection and contact models. Prerequisite: 281, 331A,B, or equivalent.

3 units, Spr (Delp, S)

ME 491. Ph.D. Teaching Experience

Required of Ph.D. students. May be repeated for credit.

3 units, Aut (Staff), Win (Staff), Spr (Staff), Sum (Staff)

ME 500. Thesis (Ph.D.)

2-15 units, Aut (Staff), Win (Staff), Spr (Staff), Sum (Staff)

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