Cholangiocarcinoma

Overview: 

MRI may suggest alternative diagnoses or determine extent of cholangiocarcinomas, assessing extent of the tumor within the bile ducts, lobar atrophy, vascular invasion, and metastatic disease. In particular, MRI may be valuable in identifying isolated bile ducts that are not delineated on more invasive studies such as ERCP or percutaneous cholangiography.

Iron Quantification

Overview: 

Hepatic and myocardial iron quantification can be performed noninvasively with MRI. MRI can quantify a parameter called "T2*", which is an indicator of the amount of iron in the liver and myocardium. The smaller the T2*, the greater then iron deposition. For exams performed on 1.5 Tesla magnets, T2* < 5 milliseconds indicates severe iron overload, 5 < T2* < 10 milliseconds indicates moderate iron overload, 10 < T2* < 20 milliseconds reflects mild overload, and T2* > 20 milliseconds is normal.

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