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Department of Neurosurgery Stanford School of Medicine
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Research Programs

Profiles of Programs

The Department of Neurosurgery is continually involved in basic science and clinical research projects to investigate the causes, mechanisms, and treatment of a number of neurological diseases. The goal of these projects is to develop new insights into disease mechanisms, which can be used to create effective new treatments and to test the efficacy and safety of these novel treatments in clinic. This usually involves multidisciplinary collaboration among basic research laboratories and multiple clinical subspecialties.

Stanford neurosurgery faculties are currently engaged in a number of clinical research projects, including:

  • New radiosurgical techniques to treat patients with brain metastases, skull
    base meningiomas and acoustic neuromas in order to preserve hearing;

  • A pallidotomy trial for movement disorders, including Parkinson's Disease and juvenile dystonia, that maps the patient's anatomy to accurately target the surgical site;

  • New techniques of intratumoral irradiation; clinical trials using NMDA receptor
    antagonists and other neuroprotective agents in head injury patients;

  • Multi-modality therapy that utilizes embolization, microsurgery and stereotactic
    radiosurgery for complex intracranial vascular malformations;

  • Evaluating surgical and non-surgical treatments for infants with
    craniosynostosis;

  • Improved methods of evaluating and treating patients with medically intractable
    epilepsy;

  • A molecular-genetic study that isolates the locus associated with familial central nervous system vascular malformations;

  • Evaluating the outcomes of cervical fusion instrumentation;

  • A multi-center study of patients with unruptured intracranial aneurysms; and

  • Neurotransplantation to treat stroke.

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