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Profiles of Programs
The Department of Neurosurgery is continually involved in basic
science and clinical research projects to investigate the causes,
mechanisms, and treatment of a number of neurological diseases.
The goal of these projects is to develop new insights into disease
mechanisms, which can be used to create effective new treatments
and to test the efficacy and safety of these novel treatments in
clinic. This usually involves multidisciplinary collaboration among
basic research laboratories and multiple clinical subspecialties.
Stanford neurosurgery faculties are currently engaged in a number
of clinical research projects, including:
- New radiosurgical techniques to treat patients with brain metastases,
skull
base meningiomas and acoustic neuromas in order to preserve hearing;
- A pallidotomy trial for movement disorders, including Parkinson's
Disease and juvenile dystonia, that maps the patient's anatomy
to accurately target the surgical site;
- New techniques of intratumoral irradiation; clinical trials
using NMDA receptor
antagonists and other neuroprotective agents in head injury patients;
- Multi-modality therapy that utilizes embolization, microsurgery
and stereotactic
radiosurgery for complex intracranial vascular malformations;
- Evaluating surgical and non-surgical treatments for infants
with
craniosynostosis;
- Improved methods of evaluating and treating patients with medically
intractable
epilepsy;
- A molecular-genetic study that isolates the locus associated
with familial central nervous system vascular malformations;
- Evaluating the outcomes of cervical fusion instrumentation;
- A multi-center study of patients with unruptured intracranial
aneurysms; and
- Neurotransplantation to treat stroke.
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