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Chemistry Faculty :
Faculty Research Interests Samir Safi
Principal Research Interests
Since biosensors were first presented in the 1980's the technology evolved to continuous analysis systems and became more and more sophisticated. In the field of metal analysis most of these systems were based on ionophores lacking both selectivity and specificity. Recently, the use of antibodies in immunosensors has been of great interest for their high selectivity. The goal of my research is to develop such tools combining antibodies and sensitive analytical detection methods. Representative Publications
1) “Synthesis and Characterization of Immunogens Based on Calix[4]arene-crown for the Generation of Antibodies Directed Towards Cesium Ions,” Safi, S.; Asfari, Z.; Ehret-Sabatier, L.; Leroy, M.; Hagege, A., Bioconjugate Chem. 17(5), 1346 (2006). 2) “Characterization of protein conjugates using capillary electrophoresis,” Safi, S.; Asfari, Z.; Hagege, A., J. Chromat. A 1173(1-2), 15 (2007). 3) “Design and characterization of immunogens for antibodies directed towards alkali metals,” Safi, S.; Asfari, Z.; Basset, C.; Quéméneur; E., Vidaud C., Hagège A., Analyst 134, 256-260 (2009). 4) “Hyphenated CE-ICP/MS using a direct injection nebulizer for Arsenic Speciation,” Safi, S.; Asfari, Z.; Hagege, A., Online Thesis Server , (2008). |
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