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3rd Annual Merck Symposium
Merck Speaker: About Evans: David A. Evans was born in Washington D.C. in 1941. He received his A.B. degree from Oberlin College in 1963 where he concentrated in physical chemistry and mathematics. He subsequently obtained his Ph.D. at the California Institute of Technology in 1967, where he worked under the direction of Professor Robert E. Ireland in the general area of organic synthesis. In that year he joined the faculty at the University of California, Los Angeles. In 1973 he was promoted to the rank of Full Professor and shortly thereafter returned to Caltech where he remained until 1983. In that year he joined the Faculty in the Chemistry Department at Harvard University and in 1990 he was appointed as the Abbott and James Lawrence Professor of Chemistry. In July of 1998 he completed his three-year term as chair of the Harvard Department of Chemistry and Chemical Biology. Professor Evans is a recipient of honors such as the ACS Award for Creative Work in Synthetic Organic Chemistry (1982), and the Arthur C. Cope Scholar Award (1988), the Yamada Prize (1997), the Tetrahedron Prize (1998), the Robert Robinson Award (1998), the Tetrahedron Prize (1998), the Prelog Medal (1999), and the Arthur C. Cope Award (2000), the Caltech Distinguished Alunmi Award (2002), the Nagoya Medal (2003), the Karl Ziegler Prize, Max Planck Institute (2003), the Willard Gibbs Medal (2005), the Noyori Prize (2006), the Glenn Seaborg Medal (2006), and the H. C. Brown Award (2007). He was elected into the National Academy of Sciences in 1984, the American Academy of Arts and Sciences in 1988. Professor Evans has made significant advances in the design of stereoselective reactions and the applications of these reactions to natural products synthesis. Over the last two decades, reaction methodology directed toward achieving absolute stereocontrol in carbon-carbon bond forming reactions has been one of the central themes that have been developed in his laboratory. Enantioselective Diels-Alder, Michael, and aldol reactions are but three of the important families of processes developed in his group. In the area of synthesis design, the Evans Group was the first to achieve the de novo synthesis of complex natural products through the exclusive use of chiral auxiliaries to control stereochemical relationships. This represented a significant departure from the more prevalent reliance on the "chiral pool" for the origins of absolute stereocontrol within the target structure. Evans' chiral auxiliaries and chiral catalysts for enantioselective bond constructions are widely used in both industrial and academic laboratories throughout the world. Professor Evans has trained more than 200 coworkers, 67 of which are now active in the worldwide academic community. About the Merck Symposium:
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