Student Hosted Colloquium

Thursday, January 24th
Professor Andrei Tokmakoff
"2D IR Spectroscopy of Protein Conformational Dynamics"

4:15pm - 5:15pm
Braun Lecture Hall
S.G.Mudd Chemistry Building
Stanford University




This seminar is free and open to the public. All Stanford University Chemistry students are encouraged to attend this special event.

About the seminar:
Infrared spectroscopy of amide transitions has great potential for studying the structure and dynamics of proteins, but this requires a quantitative understanding of the IR spectroscopy of protein secondary and tertiary structures. We are using 2D IR spectroscopy of amide transitions to understand the structural basis of collective amide vibrations in model peptides. Also, vibrational couplings from hydrogen-bonding are being studied as a signature of different conformations. 2D IR spectroscopy is also being used to statistically analyze the conformation and conformational dynamics of small peptides. 2D IR spectra lend themselves to describe structural variation, and this can be used to describe the state of denatured proteins.


About Tokmakoff:
Professor Tokmakoff received his BS in chemistry from CSU Sacramento and did his graduate studies at Stanford with Professor Fayer. He joined the Chemistry faculty of MIT in 1998 and is currently a full professor.

Questions
Please contact Patricia Dwyer at 650-723-4770.