Margaret L. Brandeau

Research Interests

1. Health Policy Modeling
2. Bioterrorism Preparedness Planning
3. Operations Management
4. Management Science Applications

1. Health Policy Modeling

Books and Reports

Kaplan, E.H. and M.L. Brandeau (Editors), Modeling the AIDS Epidemic: Planning, Policy and Prediction, Raven Press, New York, NY, 1994.

Brandeau, M.L., Sainfort, F., and W.P. Pierskalla, Eds., Operations Research and Health Care: A Handbook of Methods and Applications, Kluwer Academic Publishers, 2004.

Institute of Medicine Committee on the Prevention and Control of Viral Hepatitis Infections. Hepatitis and Liver Cancer: A National Strategy for Prevention and Control of Hepatitis B and C. National Academies Press, Washington, DC, 2010.

Institute of Medicine Committee on Prepositioned Medical Countermeasures. Prepositioning Antibiotics for Anthrax. National Academies Press, Washington, DC, 2011.

Articles

Brandeau, M.L., Lee, H.L., Owens, D.K., Sox, C.H., and R.M. Wachter, "Policy Analysis of Human Immunodeficiency Virus Screening and Intervention: A Review of Modeling Approaches", AIDS and Public Policy Journal, 5 (Summer 1990), 119-131.

Brandeau, M.L., Lee, H.L., Owens, D.K., Sox, C.H., and R.M. Wachter, "Modeling Human Immunodeficiency Virus Screening and Intervention: Analysis of Screening Policies to Reduce HIV Transmission to Newborns", Interfaces, 21 (May - June 1991), 5 - 25.

Wachter, R.M., M. Cooke, M.L. Brandeau, and D.K. Owens, "HIV Testing of Pregnant Women and Newborns" (letter), Journal of the American Medical Association, 265 (March 27, 1991), 1525.

Brandeau, M.L., Owens, D.K., Sox, C.H., and R.M. Wachter, "Screening Women of Childbearing Age for Human Immunodeficiency Virus: A Cost-Benefit Analysis", Archives of Internal Medicine, 152 (1992), 2229-2237.

Brandeau, M.L., Owens, D.K., Sox, C.H., and R.M. Wachter, "Screening Women of Childbearing Age for Human Immunodeficiency Virus: A Model-Based Policy Analysis", Management Science, 39 (1993), 72-92.

Kaplan, E.H. and M.L. Brandeau, "AIDS Policy Modeling by Example", AIDS, 8 (1994), Suppl 1, S333-S340.

Brandeau, M.L. and D.K. Owens, "When Women Return to Risk: Costs and Benefits of HIV Screening in the Presence of Relapse", in Modeling the AIDS Epidemic: Planning, Policy and Prediction, edited by E.H. Kaplan and M.L. Brandeau, Ch.8, 121-136, Raven Press, New York, NY, 1994.

Richter, A., Brandeau, M.L. and D.K Owens, "Policy Analysis of Preventive HIV Interventions Targeted to Adolescents", Simulation in the Medical Sciences Conference: Proceedings of the 1996 Western Multiconference, Society for Computer Simulation, San Diego, 1996, 55-63.

Friedrich, C.M. and M.L. Brandeau, "Using Simulation to Find Optimal Funding Levels for HIV Prevention Programs with Different Costs and Effectiveness", Proceedings of the 1998 Medical Sciences Simulation Conference, Society for Computer Simulation, San Diego, 1998, 58-64.

Zaric, G.S., Brandeau, M.L., Bayoumi, A.M., and D.K. Owens, "Simulating the Effects of Protease Inhibitors on the HIV Epidemic: Treatment, Compliance, and Drug Resistance", Proceedings of the 1998 Medical Sciences Simulation Conference, Society for Computer Simulation, San Diego, 1998, 65-72.

Brandeau, M.L., "AIDS Policy Modeling: A Social Role for Operations Research", Ricerca Operativa, 27 (1998), 5-33.

Kahn, J.G., Brandeau, M.L. and J. Dunn-Mortimer, "OR Modeling and AIDS Policy: From Theory to Practice", Interfaces, 28 (1998), 3-22.

Owens, D.K., Brandeau, M.L. and C.H. Sox, "Effect of Relapse to High-Risk Behavior on the Costs and Benefits of a Program to Screen Women for HIV", Interfaces, 28 (1998), 52-74.

Zaric, G.S., Brandeau M.L., Bayoumi, A.M., and D.K. Owens, "The Effect of Protease Inhibitors on the Spread of HIV and the Development of Drug Resistance: A Simulation Study", Simulation, 71 (1998), 262-275.

Richter, A. and M.L. Brandeau, "An Analysis of Optimal Resource Allocation for HIV Prevention Among Injection Drug Users and Nonusers", Medical Decision Making, 19 (1999), 167-179.

Zaric, G.S., Barnett, P.G., and M.L. Brandeau, "Methadone Maintenance and HIV Prevention: A Cost-Effectiveness Analysis", American Journal of Public Health, 90 (2000), 1100-1111.

Zaric, G.S., Brandeau, M.L., and P.G. Barnett, "HIV Transmission and the Cost Effectiveness of Methadone Maintenance", Management Science, 46 (2000), 1013-1031.

Zaric, G.S., Bayoumi, A.M., Brandeau, M.L. and D.K. Owens, "Routine HIV Screening of Newborns in the United States: A Cost-Effectiveness Analysis", Journal of AIDS and Human Retrovirology, 25 (2000), 403-416.

Brandeau, M.L., "Difficult Choices, Urgent Needs: Optimal Investment in HIV Prevention Programs," Quantitative Evaluation of HIV Prevention Programs, E.H. Kaplan, R. Brookmeyer, Eds., Yale University Press, 2001, pp. 128-153.

Rauner, M. and M.L. Brandeau, "AIDS Policy Modeling for the 21st Century: An Overview of Key Issues", Health Care Management Science, 4 (2001), 165-180.

Zaric, G.S. and M.L. Brandeau, "Resource Allocation for Epidemic Control Over Short Time Horizons", Mathematical Biosciences, 171 (2001), 33-58.

Barnett, P.G., Zaric, G.S., and M.L. Brandeau, "The Cost Effectiveness of Buprenorphine Maintenance Therapy for Opiate Addiction in the United States", Addiction, 96 (2001), 1267-1278.

Zaric, G.S. and M.L. Brandeau, "Optimal Investment in a Portfolio of HIV Prevention Programs", Medical Decision Making, 21 (2001), 391-408.

Zaric, G.S. and M.L. Brandeau, "Dynamic Resource Allocation for Epidemic Control in Multiple Populations", Mathematical Medicine and Biology 19 (2002), 235-255.

Brandeau, M.L., G.S. Zaric, and A. Richter, "Resource Allocation for Control of Infectious Diseases in
Multiple Independent Populations: Beyond Cost-Effectiveness Analysis", Journal of Health Economics, 22 (2003), 575-598.

Brandeau, M.L., Zaric, G.S., and V. de Angelis, "Improved Allocation of HIV Prevention Resources: Using Information About Prevention Program Production Functions", Health Care Management Science, 8 (2005), 19-28

Duriseti, R.S., Shachter, R.D., and M.L Brandeau, "Value of Quantitative D-dimer Assays in Identifying Pulmonary Embolism: Implications from a Sequential Decision Model", Academic Emergency Medicine, 13 (2006), 755-766.

Long, E.F., Brandeau, M.L., Galvin, C.M., Vinichenko, T., Tole, S.P., Schwartz, A., Sanders, G.D., and D.K. Owens. "Effectiveness and Cost-effectiveness of Expanded Antiretroviral Therapy in St. Petersburg, Russia", AIDS, 20 (2006), 2207-2215.

Long, E.F., Brandeau, M.L., Galvin, C.M., Vinichenko, T., Tole, S.P., Schwartz, A., Sanders, G.D., and D.K. Owens. "Оценка эффективности и экономической эффективности стратегии расширенной антиретровирусной терапии в Санкт-Петербурге, Россия", AIDS, 20 (2006), 2207-2215.

Zaric, G.S. and M.L. Brandeau, "A Little Planning Goes a Long Way: Multi-level Allocation of HIV Prevention Resources", Medical Decision Making, 27 (2007), 71-81.

Armbruster, B. and M.L. Brandeau, "Optimal mix of screening and contact tracing for endemic diseases", Mathematical Biosciences, 209 (2007), 386-402.
 
Brandeau, M.L., Long, E.F., Hutton, D.W., and D.K. Owens, "Optimal spending on HIV prevention and treatment: A framework for evaluating the cost-effectiveness of HIV prevention and treatment programs with example application to The India AIDS Initiative", In G.J. Lim and E.K. Lee (Eds.), Optimization in Medicine and Biology, Taylor and Francis Publishers, 2007, 147-175.
 
Hutton, D.W., Tan, D., So, S., and M.L. Brandeau, "Cost effectiveness of Hepatitis B screening and vaccination among adult Asian and Pacific Islanders in the United States", Annals of Internal Medicine, 147 (2007), 460-469.
 
Armbruster, B. and M.L. Brandeau, "Contact tracing to control infectious disease: When enough is enough", Health Care Management Science, 10 (2007), 341-355.

Zaric, G.S., Bayoumi, A.M., Brandeau, M.L., and D.K. Owens, "The Cost Effectiveness of Strategies to Improve Adherence to Highly Active Antiretroviral Therapy", Medical Decision Making, 28 (2008), 359-376.

Long, E.F., Vaidya, N., and M.L. Brandeau, "Controlling Co-epidemics: Analysis of HIV and Tuberculosis Infection Dynamics", Operations Research, 56 (2008), 1366-1381.

Brandeau, M.L. and G.S. Zaric, "Optimal Investment in HIV Prevention Programs: More Is Not Always Better", Health Care Management Science, 12 (2009), 27-37.

Tole, S.P., Sanders, G.D., Bayoumi, A.M., Galvin, C.M., Vinichenko, T.N., Brandeau, M.L., and D.K. Owens, "Cost-Effectiveness of Voluntary HIV Screening in Russia", International Journal of STD and AIDS, 20 (2009), 46-51.

Long, E.F., Brandeau, M.L. and D.K. Owens, "Potential Population Health Outcomes and Expenditures of HIV Vaccination Strategies in the United States," Vaccine, 27 (2009), 5402-5410.

Hutton, D.W., So, S.K, and M.L. Brandeau. "Cost Effectiveness of Nationwide Hepatitis B Catch-up Vaccination Among Children and Adolescents in China", Hepatology, 51 (2010), 405-414.

Armbruster, B. and M.L. Brandeau. "Cost-effective Control of Chronic Viral Diseases: Finding the Optimal Level of Screening and Contact Tracing ", Mathematical Biosciences, 34 (2010), 35-42.

Bendavid, E., Brandeau, M.L., Wood, R., and D.K. Owens. "Comparative Effectiveness of HIV Testing and Treatment in Highly Endemic Regions," Archives of Internal Medicine, 170 (2010), 1347-1354.

Duriseti, R.S. and M.L. Brandeau. "Cost-Effectiveness of Strategies for Diagnosing Pulmonary Embolism Among Emergency Department Patients Presenting with Undifferentiated Symptoms," Annals of Emergency Medicine, 56 (2010), 321-332.

Long, E.F., Brandeau, M.L. and D.K. Owens, "HIV Epidemic Control: Population Health Outcomes and Costs of Expanded HIV Screening and Antiretroviral Treatment in the United States," Annals of Internal Medicine, 153 (2010), 778-789.

Hutton, D.W., Brandeau, M.L. and S.K. So. "Doing Good with Good OR: Supporting Cost-effective Hepatitis B Interventions," Interfaces, 41 (2011), 289-300.

Alistar, S.S, Owens, D.K., and M.L. Brandeau, "Effectiveness and Cost Effectiveness of Expanding Harm Reduction and Antiretroviral Therapy in a Mixed HIV Epidemic: A Modeling Analysis for Ukraine," PLoS Medicine, 8 (2011), e1000423.

Alistar, S.S, Owens, D.K., and M.L. Brandeau, "Результативность и экономическая эффективность расширения программ снижения вреда и антиретровирусной терапии при «смешанной» эпидемии ВИЧ: анализ модели на примере Украины," PLoS Medicine, 8 (2011), e1000423.

Enns, E.A. and M.L. Brandeau, "Inferring Model Parameters in Network-Based Disease Simulation," Health Care Management Science, 14 (2011), 174-188.

Enns, E.A., Brandeau, M.L., Igeme, T.K., and E. Bendavid, "Assessing Effectiveness and Cost Effectiveness of Concurrency Reduction for HIV Prevention," International Journal of STD and AIDS, 22 (2011), 558-567.

Juusola, J.L., Brandeau, M.L., Long, E.F., Owens, D.K., and E. Bendavid, "The Cost-Effectiveness of Symptom-Based Testing and Routine Screening for Acute HIV Infection in Men Who Have Sex with Men in the United States," AIDS, 25 (2011), 1779-1787.

Alistar, S.S. and M.L. Brandeau. "Decision Making for HIV Prevention and Treatment Scale Up: Bridging the Gap Between Theory and Practice," Medical Decision Making, 32 (2012), 105-117.

Enns, E.A., Mounzer, J.J., and M.L. Brandeau. "Optimal Link Removal for Epidemic Mitigation: A Two-Way Partitioning Approach, "Mathematical Biosciences, in press.

Juusola, J.L., Brandeau, M.L., Owens, D.K., and E. Bendavid. "The Cost-Effectiveness of Preexposure Prophylaxis for HIV Prevention in Men Who Have Sex with Men in the United States," Annals of Internal Medicine, in press.

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2. Bioterrorism Preparedness Planning

Bravata, D.M., McDonald, K., Owens, D.K., Wilhelm, E., Brandeau, M.L., Zaric, G.S., Holty, J-E.C., Liu, H., and V. Sundaram, Regionalization of Bioterrorism Preparedness and Response (Evidence Report/Technology Assessment). Agency for Healthcare Research and Quality, Rockville, MD, 2003.

Bravata, D.M., Zaric, G.S., Holty, J-E.C., Brandeau, M.L., Wilhelm, E.R., McDonald, K.M., and D.K. Owens, “Reducing Mortality from Anthrax Bioterrorism: Costs and Benefits of Alternative Strategies for Stockpiling and Dispensing Medical and Pharmaceutical Supplies,” Biosecurity and Bioterrorism, Biodefense Strategy, Practice and Science, 4 (2006), 244-262.

Brandeau, M.L., Hutton, D.M., Owens, D.K., and D.M. Bravata, "Planning The Bioterrorism Response Supply Chain: Learn and Live," American Journal of Disaster Medicine, 2 (2007), 231-248.

Zaric, G.S., Bravata, D.M., Holty, J-E.C., McDonald, K.M., Owens, D.K. and M.L. Brandeau, Modeling the Logistics of Response to Anthrax Bioterrorism, Medical Decision Making, 28 (2008), 332-250.

Brandeau, M.L., Zaric, G.S., Freiesleben, J., Edwards, F.L., and D.M. Bravata, "An Ounce of Prevention Is Worth a Pound of Cure: Improving Communication to Reduce Mortality During Bioterrorism Responses," American Journal of Disaster Medicine, 3 (2008), 65-78.

Brandeau, M.L., McCoy, J.H., Hupert, N.A., Holty, J-E., and D.M. Bravata, "Recommendations for Modeling Crisis Response in Public Health and Medicine: A Position Paper of the Society for Medical Decision Making," Medical Decision Making, 29 (2009), 438-460.

Institute of Medicine Committee on Prepositioned Medical Countermeasures. Prepositioning Antibiotics for Anthrax. National Academies Press, Washington, DC, 2011.

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3. Operations Management

Printed Circuit Board Process Design

Brandeau, M.L. and C.A. Billington, "Design of Manufacturing Cells: Operation Assignment in Printed Circuit Board Manufacturing," Journal of Intelligent Manufacturing, 2 (1991), 95-106.

Hillier, M.S. and M.L. Brandeau, "Optimal Operation Assignment and Product Grouping in Printed Circuit Board Manufacturing," Operations Research, 46 (1998), 675-689.

Hillier, M.S. and M.L. Brandeau "Cost Minimization and Workload Balancing in Printed Circuit Board Assembly," IIE Transactions, 33 (2001), 547-557.

Design of Shop Floor Material Handling Systems

Johnson, M.E. and M.L. Brandeau, "An Analytic Model for Design of a Multi-Vehicle Automated Guided Vehicle System," Management Science, 39 (1993), 1477-1489.

Johnson, M.E. and M.L. Brandeau, "Application of Analytic Models for Material Handling System Design: Analysis of Stochastic Effects," in Progress in Material Handling Research, Braun-Brumfield, Inc., Ann Arbor, MI, 1993, 97-120.

Johnson, M.E. and M.L. Brandeau, "An Analytic Model for Design and Analysis of Single-Vehicle Asynchronous Material Handling Systems," Transportation Science, 28 (1994), 337-353.

Johnson, M.E. and M.L. Brandeau, "Designing Multiple-Load Automated Guided Vehicle Systems for Delivering Material from a Central Depot," Transactions of the ASME: Journal of Engineering for Industry, 117 (1995), 33-41.

Johnson, M.E. and M.L. Brandeau, "Stochastic Modeling for Automated Material Handling System Design and Control," Transportation Science, 30 (1996), 330-350.

Thonemann, U.W. and M.L. Brandeau, "Designing a Single-Vehicle Automated Guided Vehicle System with Multiple-Load Capacity," Transportation Science, 30 (1996), 351-363.

Thonemann, U.W. and M.L. Brandeau, "Designing a Zoned Automated Guided Vehicle System with Multiple Vehicles and Multiple Load Capacity," Operations Research, 45 (1997), 857-873.

Thonemann, U.W. and M.L. Brandeau, "Note: Optimal Storage Assignment Policies for Automated Storage and Retrieval Systems with Stochastic Demands," Management Science, 44 (1998), 142-148.

Johnson, M.E. and M.L. Brandeau, "Design of an Automated Shop Floor Material Handling System with Inventory Considerations," Operations Research, 47 (1999), 65-80.

Product Design

Thonemann, U.W. and M.L. Brandeau, "Optimal Commonality in Component Design," Operations Research, 48 (2000), 1-19.

Humanitarian Logistics

McCoy, J.H and M.L. Brandeau, "Efficient Stockpiling and Shipping Strategies for Humanitarian Relief: UNHCR’s Inventory Challenge," OR Spectrum, 33 (2011), 673-698.

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4. Management Science Applications

Brandeau, M.L. and R.C. Larson, "Extending and Applying the Hypercube Queueing Model to Deploy Ambulances in Boston," in Management Science and the Delivery of Urban Service, edited by E. Ignall and A.J. Swersey, TIMS Studies in the Management Sciences Series, Vol. 22, 121-154, North-Holland/Elsevier, 1986.

Brandeau, M.L., S.S. Chiu, and R. Batta, "Locating the Two-Median of a Tree Network with Continuous Link Demands," Annals of Operations Research, 6 (1986), 223-253.

Brandeau, M.L. and S.S. Chiu, "Parametric Facility Location on a Tree Network with an Lp Norm Cost Function," Transportation Science, 22 (1988), 59-69.

Brandeau, M.L. and S.S. Chiu, "Establishing Continuity of Certain Optimal Parametric Facility Location Trajectories," Transportation Science, 22 (1988), 224-225.

Brandeau, M.L. and S.S. Chiu, "An Overview of Representative Problems in Location Research," Management Science, 35 (1989), 645-674.

Brandeau, M.L. and S.S. Chiu, "Trajectory Analysis of the Stochastic Queue Median in a Plane with Rectilinear Distances," Transportation Science, 24 (1990), 230-243.

Brandeau, M.L. and S.S. Chiu, "A Unified Family of Queuing-Location Models," Operations Research, 38 (1990), 1034-1044.

Brandeau, M.L. and S.S. Chiu, "Parametric Analysis of Optimal Facility Locations," Networks, 21 (1991), 223-243.

Brandeau, M.L. and S.S. Chiu, "A Center Location Problem with Congestion," Annals of Operations Research, 40 (1992), 17-32.

Brandeau, M.L., "Characterization of the Stochastic Queue Median Trajectory in a Plane with Generalized Distances," Operations Research, 40 (1992), 331-341.

Brandeau, M.L. and S.S. Chiu, "Sequential Location and Allocation: Worst Case Performance and Statistical Estimation," Location Science, 1 (1993), 289-298.

Brandeau, M.L. and S.S. Chiu, "Location of Competing Private Facilities in a User-Optimizing Environment with Market Externalities," Transportation Science, 28 (1994), 125-140.

Brandeau, M.L. and S.S. Chiu, "Facility Location in a User-Optimizing Environment with Market Externalities: Analysis of Customer Equilibria and Optimal Public Facility Location," Location Science, 2 (1994), 129-147.

Brandeau, M.L., Chiu, S.S., Kumar, S., and T.A. Grossman, "Location with Market Externalities," in Facility Location: A Survey of Applications and Methods, edited by Z. Drezner, Ch. 7, 121-150, Springer-Verlag, New York, NY, 1995.

Grossman, T.A. and M.L. Brandeau, "Optimal Pricing for Service Facilities with Self-Optimizing Customers," European Journal of Operational Research, 141 (2002), 39-57.

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