The Life Cycle of Oesophagostomum
- Fast Facts
Eggs are passed into the feces and
hatch into L1.
L1 develop into infective L3 in
the environment in 6-7 days.
L3 are ingested and end up in the
Larvae exsheath in the S.I. and
penetrate the wall, forming nodules.
Possible Life Cycle of Oesophagostomum
Life Cycle Uncertainty in
Although the life cycle for Oesophagostomiasis has been characterized for
animals, the route of transmission and infectivity are unknown for humans.
It is hypothesized that, because this disease is a zoonosis, the
parasite's life cycle is similar to the life cycle seen in animals like
sheep, goats, and cows (see below). One distinct difference in the
parasitic life cycle during human infection is that the eggs are usually
not transmitted out of the body along with the feces. This is because the
parasite is unable to complete its life cycle of penetrating the
intestinal wall and the nodules in which it has become encapsulated.
it is hypothesized that transmission between humans is low and that the
majority of the infections are a result of soil contamination by
livestock. This explanation fails to explain the localization of the
disease though. It is important to note that the parasite's inability to
complete its life cycle is actually one of the causes of disease.
Confirmed Life Cycle of Oesophagostomum
Borrowed from Colin Johnstone's lecture
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