The Discovery of F. buski: A History of Misdiagnosis


1843 English surgeon George Busk finds 14 flukes in the duodenum of a sailor from eastern India during an autopsy. The discovery is not published, however.

1852 Discovery is briefly noted in Diseases of the Liver by George Budd.

1857 In his translation of On Animal and Vegetable Parasites, ER Lankester refers to the discovery and names the agent Distoma Buskii after its discoverer. Busk objected and suggested the name Distoma crassum, which was adopted in subsequent publications. Controversy shortly ensues when it is discovered that D. crassum had already been used in 1836 to describe another parasite. Everyone loses interest until the parasite resurfaces in 1874.

1874 A missionary and his wife residing in China consult an English doctor about persistent diarrhea and are treated for various well-known diseases without success. Eventually, 12 worms are found in their stool and showed to Busk, who immediately recognizes them as the species he had discovered years before. At the same time, a worm passed in the vomit of a 15 year-old Chinese boy makes its way to English parasitologists and is misidentified twice as similar species. The mistake is not corrected for many years.

1887 J Poirier describes a worm passed by a 35 year old Chinese woman as the D. crassum discovered by Busk, many parasitologists argue that it is not.

1902 Odhner examines fluke samples from a Chinese boy, expelled in 1890, and improves on the description assigning them to the genus Fasciolopsis (Latin: Fasciola, fillet; Greek: opsis, resembling). He names the worms in question Fasciolopsis buski. This work, however, passes under the radar of most parasitologists at the time.

1908 A fluke passed by an eight year old Chinese girl is named Kwan's Fluke after its supposed discoverer, but is later revealed to be Busk's D. crassum damaged by intestinal juices.

1909 Flukes pass from a sailor from Calcutta, originally diagnosed as having Typhoid fever. E Rodenwaldt believes they are a new species and calls them F. fulleborni.

1917 Brown studies samples of these flukes and renames them F. spinifera after the characteristic cuticle spines.

1919 All the confusion comes to an end when KW Goddard at the Christian Hospital in Shaohsing, China studies over 400 samples of the flukes and conforms to the names F. buski, F. goddardi, and F. rathouisi for three variants of the worm.

The mysterious universe inside holds many astonishing secrets.
Image taken from The Elvis Presley Organization
HOME