Research Areas (all)Publication TypeYears
CHRChromatin   DATAData
DYNDynamics   EVOLEvolution
EXPExpression   FUNFunction
GIGenetic-Interaction   METMetabolic
NSNetwork-Structure   P2PP2P
RECReconstruction   REGRegulatory
REVReview   SIGSignaling
TRANSTranscription  
JJournal Article
CConference Paper
BBook
ChBook Chapter
TTechnical Report
PhDPhD Disseration
2000 - 2000
2001 - 2001
2002 - 2002
2003 - 2003
2004 - 2004
2005 - 2005
2006 - 2006

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topics: CHRDATADYNEVOLEXPFUNGIMETNSP2PRECREGREVSIGTRANS

2006
J   Jensen, Lars J., Jensen, Thomas S., de Lichtenberg, Ulrik, Brunak, S., and Bork, Peer (2006). "Co-evolution of transcriptional and post-translational cell-cycle regulation." Nature. PDF bib
topics:       DYN EVOL                P2P          SIG TRANS

J   Chua, G., Morris, Q. D., Sopko, R., Robinson, M. D., Ryan, O., Chan, E. T., Frey, B. J., Andrews, B. J., Boone, C., and Hughes, T. R. (2006). "Identifying transcription factor functions and targets by phenotypic activation.." Proc Natl Acad Sci U S A, 103, 12045-12050. PDF bib
topics:    DATA       EXP                REC          TRANS

J   Beyer, A., Workman, C., Hollunder, J., Radke, D., Mauller, U., Wilhelm, T., and Ideker, T. (2006). "Integrated assessment and prediction of transcription factor binding.." PLoS Comput Biol, 2. PDF bib
topics:                               REC          TRANS

J   Ho, Su-Wen W., Jona, Ghil, Chen, Christina T L T., Johnston, Mark, and Snyder, Michael (2006). "Linking DNA-binding proteins to their recognition sequences by using protein microarrays.." Proc Natl Acad Sci U S A. PDF bib
topics:    DATA                                     TRANS

J   Balaji, S., Iyer, L. M., Aravind, L., and Babu, M. M. (2006). "Uncovering a hidden distributed architecture behind scale-free transcriptional regulatory networks.." J Mol Biol, 360, 204-212. PDF bib
topics:                         NS                TRANS

J   Tanay, Amos (2006). "Extensive low-affinity transcriptional interactions in the yeast genome.." Genome Res. PDF bib
topics:                               REC          TRANS

J   Workman, Christopher T., Mak, Craig H., Mccuine, Scott, Tagne, Jean-Bosco, Agarwal, Maya, Ozier, Owen, Begley, Thomas J., Samson, Leona D., and Ideker, Trey (2006). "A Systems Approach to Mapping DNA Damage Response Pathways." Science, 312, 1054-1059. PDF bib
topics:                FUN             REC          TRANS

J   Nguyen, Dat H. and D'Haeseleer, Patrik (2006). "Deciphering principles of transcription regulation in eukaryotic genomes." Mol Syst Biol, 2, msb4100054-E1-msb4100054-E10. PDF bib
topics:          EVOL                               TRANS

J   Borneman, A. R., Leigh-Bell, J. A., Yu, H., Bertone, P., Gerstein, M., and Snyder, M. (2006). "Target hub proteins serve as master regulators of development in yeast.." Genes Dev, 20, 435-448. PDF bib
topics:                         NS                TRANS

J   Blanchette, M., Bataille, A.R., Chen, X., Poitras, C., Laganiere, J., Lefebvre, C., Deblois, G., Giguere, V., Ferretti, V., Bergeron, D., and others (2006). "Genome-wide computational prediction of transcriptional regulatory modules reveals new insights into human gene expression." Genome Research, 16, 656. PDF bib
topics:          EVOL                   REC          TRANS

J   Carninci, P., Sandelin, A., Lenhard, B., Katayama, S., Shimokawa, K., Ponjavic, J., Semple, C.A.M., Taylor, M.S., Engström, P.G., Frith, M.C., and others (2006). "Genome-wide analysis of mammalian promoter architecture and evolution." . PDF bib
topics:          EVOL                               TRANS

J   Davidson, E.H. and Erwin, D.H. (2006). "Gene Regulatory Networks and the Evolution of Animal Body Plans." Science, 311, 796. PDF bib
topics:          EVOL                               TRANS

J   Odom, D.T., Dowell, R.D., Jacobsen, E.S., Nekludova, L., Rolfe, P.A., Danford, T.W., Gifford, D.K., Fraenkel, E., Bell, G.I., and Young, R.A. (2006). "Core transcriptional regulatory circuitry in human hepatocytes." Nature. PDF bib
topics:                         NS                TRANS

J   Yeang, C.H. and Jaakkola, T. (2006). "Modeling the Combinatorial Functions of Multiple Transcription Factors." JOURNAL OF COMPUTATIONAL BIOLOGY, 13, 463. PDF bib
topics:                               REC          TRANS

J   Kim, Seon-Young and Kim, YongSung (2006). "Genome-wide prediction of transcriptional regulatory elements of human promoters using gene expression and promoter analysis data." BMC Bioinformatics, 7(1), 330. PDF bib
topics:                               REC          TRANS

J   Bar-Even, A., Paulsson, J., Maheshri, N., Carmi, M., O'Shea, E., Pilpel, Y., and Barkai, N. (2006). "Noise in protein expression scales with natural protein abundance." Nature Genetics, 38, 636-643. PDF bib
topics:             EXP                            TRANS

2005
J   Boyer, L. A., Lee, T. I., Cole, M. F., Johnstone, S. E., Levine, S. S., Zucker, J. P., Guenther, M. G., Kumar, R. M., Murray, H. L., Jenner, R. G., Gifford, D. K., Melton, D. A., Jaenisch, R., and Young, R. A. (2005). "Core transcriptional regulatory circuitry in human embryonic stem cells.." Cell, 122, 947-956. PDF bib
topics:                         NS                TRANS

J   Siggia, E. D. (2005). "Computational methods for transcriptional regulation.." Curr Opin Genet Dev, 15, 214-221. PDF bib
topics:                               REC    REV    TRANS

J   Ihmels, J., Bergmann, S., Gerami-Nejad, M., Yanai, I., McClellan, M., Berman, J., and Barkai, N. (2005). "Rewiring of the Yeast Transcriptional Network Through the Evolution of Motif Usage." Science, 309, 938-940. PDF bib
topics:          EVOL                               TRANS

J   Kafri, R., Bar-Even, A., and Pilpel, Y. (2005). "Transcription control reprogramming in genetic backup circuits." Nature Genetics, 37(3), 295-299. PDF bib
topics:                FUN GI                      TRANS

J   Kim, TH, Barrera, LO, Zheng, M., Qu, C., Singer, MA, Richmond, TA, Wu, Y., Green, RD, and Ren, B. (2005). "A high-resolution map of active promoters in the human genome.." Nature, 436(7052), 876-80. PDF bib
topics: CHR DATA                                     TRANS

J   Tanay, A., Regev, A., and Shamir, R. (2005). "Conservation and evolvability in regulatory networks: The evolution of ribosomal regulation in yeast." Proceedings of the National Academy of Sciences, 102, 7203-7208. PDF bib
topics:          EVOL                               TRANS

J   Balazsi, G., Barabasi, A.L., and Oltvai, ZN (2005). "Topological units of environmental signal processing in the transcriptional regulatory network of Escherichia coli." Proceedings of the National Academy of Sciences, 102(22), 7841-7846. PDF bib
topics:                         NS                TRANS

J   Wang, W., Cherry, J.M., Nochomovitz, Y., Jolly, E., Botstein, D., and Li, H. (2005). "Inference of combinatorial regulation in yeast transcriptional networks: A case study of sporulation." Proceedings of the National Academy of Sciences, 102(6), 1998-2003. PDF bib
topics:                               REC          TRANS

J   Zhang, L. V., King, O. D., Wong, S. L., Goldberg, D. S., Tong, A. H., Lesage, G., Andrews, B., Bussey, H., Boone, C., and Roth, F. P. (2005). "Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction network.." J Biol, 4. PDF bib
topics:                FUN       NS P2P             TRANS

2004
J   Chua, G., Robinson, M. D., Morris, Q., and Hughes, T. R. (2004). "Transcriptional networks: reverse-engineering gene regulation on a global scale.." Curr Opin Microbiol, 7, 638-646. PDF bib
topics:                               REC    REV    TRANS

J   Luscombe, N. M., Babu, M. M., Yu, H., Snyder, M., Teichmann, S. A., and Gerstein, M. (2004). "Genomic analysis of regulatory network dynamics reveals large topological changes.." Nature, 431, 308-312. PDF bib
topics:       DYN    EXP          NS                TRANS

J   Babu, M. M., Luscombe, N. M., Aravind, L., Gerstein, M., and Teichmann, S. A. (2004). "Structure and evolution of transcriptional regulatory networks.." Curr Opin Struct Biol, 14, 283-291. PDF bib
topics:          EVOL                               TRANS

J   Tanay, A., Gat-Viks, I., and Shamir, R. (2004). "A global view of the selection forces in the evolution of yeast cis-regulation.." Genome Res, 14, 829-834. PDF bib
topics:          EVOL                               TRANS

J   Beer, M. A. and Tavazoie, S. (2004). "Predicting gene expression from sequence.." Cell, 117, 185-198. PDF bib
topics:             EXP                REC          TRANS

J   Yeger-Lotem, E., Sattath, S., Kashtan, N., Itzkovitz, S., Milo, R., Pinter, R. Y., Alon, U., and Margalit, H. (2004). "Network motifs in integrated cellular networks of transcription-regulation and protein-protein interaction.." Proc Natl Acad Sci U S A, 101, 5934-5939. PDF bib
topics:                         NS P2P             TRANS

J   Gao, F., Foat, B. C., and Bussemaker, H. J. (2004). "Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data.." BMC Bioinformatics, 5. PDF bib
topics:             EXP                REC          TRANS

J   Lahav, G., Rosenfeld, N., Sigal, A., Geva-Zatorsky, N., Levine, A. J., Elowitz, M. B., and Alon, U. (2004). "Dynamics of the p53-Mdm2 feedback loop in individual cells.." Nat Genet, 36, 147-150. PDF bib
topics:                         NS             SIG TRANS

J   Ihmels, J., Levy, R., and Barkai, N. (2004). "Principles of transcriptional control in the metabolic network of Saccharomyces cerevisiae.." Nat Biotechnol, 22, 86-92. PDF bib
topics:             EXP       MET                   TRANS

J   Pritsker, Moshe, Liu, Yir-Chung, Beer, Michael A., and Tavazoie, Saeed (2004). "Whole-Genome Discovery of Transcription Factor Binding Sites by Network-Level Conservation." Genome Res., 14, 99-108. PDF bib
topics:          EVOL                   REC          TRANS

J   Gasch, A.P., Moses, A.M., Chiang, D.Y., Fraser, H.B., Berardini, M., and Eisen, M.B. (2004). "Conservation and evolution of cis-regulatory systems in ascomycete fungi." PLoS Biol, 2, e398. PDF bib
topics:          EVOL                               TRANS

J   Teichmann, S.A. and Babu, M.M. (2004). "Gene regulatory network growth by duplication." Nature Genetics, 36, 492-496. PDF bib
topics:          EVOL                               TRANS

J   Covert, M.W., Knight, E.M., Reed, J.L., Herrgard, M.J., and Palsson, B.O. (2004). "Integrating high-throughput and computational data elucidates bacterial networks." Nature, 429(6987), 92-96. PDF bib
topics:                      MET       REC          TRANS

J   Hall, D.A., Zhu, H., Zhu, X., Royce, T., Gerstein, M., Snyder, M., and Duty, D.D. (2004). "Regulation of Gene Expression by a Metabolic Enzyme." Science, 306(5695), 482-484. PDF bib
topics:                                  REG       TRANS

J   Harbison, Christopher T., Gordon, Benjamin D., Lee, Tong I., Rinaldi, Nicola J., Macisaac, Kenzie D., Danford, Timothy W., Hannett, Nancy M., Tagne, Jean-Bosco, Reynolds, David B., Yoo, Jane, Jennings, Ezra G., Zeitlinger, Julia, Pokholok, Dmitry K., Kellis, Manolis, Rolfe, Alex P., Takusagawa, Ken T., Lander, Eric S., Gifford, David K., Fraenkel, Ernest, and Young, Richard A. (2004). "Transcriptional regulatory code of a eukaryotic genome." Nature, 431, 99-104. PDF bib
topics:    DATA                                     TRANS

J   Herrgard, MJ, Covert, MW, and Palsson, BO (2004). "Reconstruction of microbial transcriptional regulatory networks.." Curr Opin Biotechnol, 15(1), 70-7. PDF bib
topics:                               REC          TRANS

J   Howard, ML and Davidson, EH (2004). "cis-Regulatory control circuits in development.." Dev Biol, 271(1), 109-18. PDF bib
topics:                         NS          REV    TRANS

J   Tanay, A. and Shamir, R. (2004). "Multilevel modeling and inference of transcription regulation.." J Comput Biol, 11, 357-375. PDF bib
topics:                               REC          TRANS

J   Yeang, C. H., Ideker, T., and Jaakkola, T. (2004). "Physical network models.." J Comput Biol, 11, 243-262. PDF bib
topics:                            P2P REC          TRANS

J   Ihmels, J., Levy, R., and Barkai, N. (2004). "Principles of transcriptional control in the metabolic network of Saccharomyces cerevisiae." Nature Biotechnology, 22(1), 86-92. PDF bib
topics:             EXP       MET                   TRANS

2003
J   Bar-Joseph, Z., Gerber, G. K., Lee, T. I., Rinaldi, N. J., Yoo, J. Y., Robert, F., Gordon, D. B., Fraenkel, E., Jaakkola, T. S., Young, R. A., and Gifford, D. K. (2003). "Computational discovery of gene modules and regulatory networks.." Nat Biotechnol, 21, 1337-1342. PDF bib
topics:                               REC          TRANS

J   Huh, W. K., Falvo, J. V., Gerke, L. C., Carroll, A. S., Howson, R. W., Weissman, J. S., and O'Shea, E. K. (2003). "Global analysis of protein localization in budding yeast.." Nature, 425, 686-691. PDF bib
topics:                            P2P             TRANS

J   Qian, J., Lin, J., Luscombe, N. M., Yu, H., and Gerstein, M. (2003). "Prediction of regulatory networks: genome-wide identification of transcription factor targets from gene expression data.." Bioinformatics, 19, 1917-1926. PDF bib
topics:             EXP                REC          TRANS

2002
J   Lee, T. I., Rinaldi, N. J., Robert, F., Odom, D. T., Bar-Joseph, Z., Gerber, G. K., Hannett, N. M., Harbison, C. T., Thompson, C. M., Simon, I., Zeitlinger, J., Jennings, E. G., Murray, H. L., Gordon, D. B., Ren, B., Wyrick, J. J., Tagne, J. B., Volkert, T. L., Fraenkel, E., Gifford, D. K., and Young, R. A. (2002). "Transcriptional regulatory networks in Saccharomyces cerevisiae.." Science, 298, 799-804. PDF bib
topics:    DATA                   NS                TRANS

J   Rajewsky, N., Vergassola, M., Gaul, U., and Siggia, E. D. (2002). "Computational detection of genomic cis-regulatory modules applied to body patterning in the early Drosophila embryo.." BMC Bioinformatics, 3. PDF bib
topics:                               REC          TRANS

J   Covert, M. W. and Palsson, B. Ø. (2002). "Transcriptional regulation in constraints-based metabolic models of Escherichia coli.." J Biol Chem, 277, 28058-28064. PDF bib
topics:                FUN    MET                   TRANS

J   Guelzim, N., Bottani, S., Bourgine, P., and Képès, F. (2002). "Topological and causal structure of the yeast transcriptional regulatory network." Nature Genetics, 31, 60-63. PDF bib
topics:                         NS                TRANS

C   Segal, E., Barash, Y., Simon, I., Friedman, N., and Koller, D. (2002). "From promoter sequence to expression: a probabilistic framework." (pp. 263-272). PDF bib
topics:             EXP                REC          TRANS

2001
J   Covert, M. W., Schilling, C. H., and Palsson, B. (2001). "Regulation of gene expression in flux balance models of metabolism.." J Theor Biol, 213, 73-88. PDF bib
topics:                FUN    MET                   TRANS

J   Pilpel, Y., Sudarsanam, P., and Church, G. M. (2001). "Identifying regulatory networks by combinatorial analysis of promoter elements.." Nat Genet, 29, 153-159. PDF bib
topics:             EXP                REC          TRANS


J   Herrg\aard, M.J., Covert, M.W., and Palsson, B.\O. (). "Reconciling Gene Expression Data With Known Genome-Scale Regulatory Network Structures." Genome Research, 13, 2423-2434. PDF bib
topics:             EXP                            TRANS


J   Kolbe, D., Taylor, J., Elnitski, L., Eswara, P., Li, J., Miller, W., Hardison, R., and Chiaromonte, F. (). "Regulatory Potential Scores From Genome-Wide Three-Way Alignments of Human, Mouse, and Rat." Genome Research, 14, 700-707. PDF bib
topics:          EVOL                               TRANS


J   Yu, H., Luscombe, N.M., Qian, J., and Gerstein, M. (). "Genome-wide analysis of gene expression relationships in transcriptional regulatory networks." Trend in Genetics, 19, 422-427. PDF bib
topics:             EXP          NS                TRANS